CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030717
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Synaptotagmin-4 
Protein Synonyms/Alias
 cDNA FLJ51713, highly similar to Synaptotagmin-4 
Gene Name
 SYT4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
40YKFVHVLKGVDIYPEubiquitination[1]
93NFPKTNLKPGSPSDLubiquitination[1]
298LKARHLPKSDVSGLSubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 407 AA 
Protein Sequence
MAPITTSREE FVSLFAWICC QRKSSKSNKT PPYKFVHVLK GVDIYPENLN SKKKFGADDK 60
NEVKNKPAVP KNSLHLDLEK RDLNGNFPKT NLKPGSPSDL ENATPKLFLE GEKESVSPES 120
LKSSTSLTSE EKQEKLGTLF FSLEYNFERK AFVVNIKEAR GLPAMDEQSM TSDPYIKMTI 180
LPEKKHKVKT RVLRKTLDPA FDETFTFYGI PYTQIQELAL HFTILSFDRF SRDDIIGEVL 240
IPLSGIELSE GKMLMNREII KRNVRKSSGR GELLISLCYQ STTNTLTVVV LKARHLPKSD 300
VSGLSDPYVK VNLYHAKKRI SKKKTHVKKC TPNAVFNELF VFDIPCEGLE DISVEFLVLD 360
SERGSRNEVI GQLVLGAAAE GTGGEHWKEI CDYPRRQIAK WHVLCDG 407 
Gene Ontology
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0008021; C:synaptic vesicle; IEA:InterPro.
 GO:0005215; F:transporter activity; IEA:InterPro. 
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR018029; C2_membr_targeting.
 IPR001565; Synaptotagmin. 
Pfam
 PF00168; C2 
SMART
 SM00239; C2 
PROSITE
 PS50004; C2 
PRINTS
 PR00399; SYNAPTOTAGMN.