CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016143
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ankyrin repeat domain-containing protein 23 
Protein Synonyms/Alias
 Diabetes-related ankyrin repeat protein 
Gene Name
 Ankrd23 
Gene Synonyms/Alias
 Darp 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
18SGERVDRKALEFGRGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression. 
Sequence Annotation
 REPEAT 144 173 ANK 1.
 REPEAT 177 206 ANK 2.
 REPEAT 210 239 ANK 3.
 REPEAT 243 272 ANK 4.
 REGION 179 196 Interaction with TTN (By similarity).  
Keyword
 ANK repeat; Coiled coil; Complete proteome; Nucleus; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 306 AA 
Protein Sequence
MDFISIEQLV SGERVDRKAL EFGRGVPDPG GWPSGWTLGP QEAVAREKLK LEEEKRKKLE 60
RFNSSRLTLD NLTDLENLVQ RRRKKRQRHK VPPREPESGA EPQPQVPLEP VGLEMFLKAA 120
AENQEALIDK YLADGGDPNA HDKLHRTALH WACLKGHRQL VNKLLAAGAA IEVRDLLDRT 180
PVFWACRGGH LDILKRLLNQ GAQVNAQDKI WSTPLHVAVR MGHSDCLEHL IECGAHINAQ 240
DKEGDTALHE AVRYGHHKAT KLLLLYGAKL GVKNVASQTP VQLARDWQRG IRDALQAHVG 300
HPRTRC 306 
Gene Ontology
 GO:0015629; C:actin cytoskeleton; IEA:Compara.
 GO:0031674; C:I band; IDA:MGI.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0006631; P:fatty acid metabolic process; IDA:MGI. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom. 
Pfam
 PF12796; Ank_2 
SMART
 SM00248; ANK 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT 
PRINTS
 PR01415; ANKYRIN.