CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027427
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Histone acetyltransferase, putative 
Protein Synonyms/Alias
  
Gene Name
 PF11_0192 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
10LGGKNENKVNVIKGAacetylation[1]
15ENKVNVIKGAGSIGKacetylation[1]
22KGAGSIGKYIMKENGacetylation[1]
145VSNKIQGKGSVSYKSacetylation[1]
151GKGSVSYKSKEKTGDacetylation[1]
153GSVSYKSKEKTGDHSacetylation[1]
164GDHSSNNKNTKGNNNacetylation[1]
167SSNNKNTKGNNNKVRacetylation[1]
172NTKGNNNKVRTSGKVacetylation[1]
178NKVRTSGKVINSLSKacetylation[1]
428SKLFLDHKTLKHRVNacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 608 AA 
Protein Sequence
MVLGGKNENK VNVIKGAGSI GKYIMKENGS KIKEVGEWNN SSENENSDNN NNDREDNIKE 60
KVDNNNKNDD NNNNDREDNI KEKVDNNNNN DDNNNDNNNN NKSDNNNNKS DNNNNKSDNY 120
NNKIGDVSNI PSTNTSTVSN KIQGKGSVSY KSKEKTGDHS SNNKNTKGNN NKVRTSGKVI 180
NSLSKYSDSY ALIFPNALPV KQVLWGLDPL NKVWRYCSIV YARPKNKVLN DTNFMFPLNM 240
NKNEIINKVN NELNNNNSVS MSEGDYDYYV HWEKFDRRLD CWLAYENLRL LDKEPDDGLP 300
LIKDNDNVSD HEHAGIDKEY LREHEENTKL KTINQIRFGK YLIDTWYFSP YPKEYQNIDI 360
LYICEFCLSF FKEYSELKRH IEKCEIRHPP GNEIYREEKI SIFEIDGSYF RIYCENLCFL 420
SKLFLDHKTL KHRVNLFLFY VITEYDEYGY HITGYFSKEK YSKNNVSCIL TLPQHQKKGY 480
GKFLINFSYF LSQTEKRTGT PERPLSDLGV ASYMAYWYET ILKVLINYEQ LSIQELSEIT 540
SIETNDIISC LEEKDIFKNS LNGLDSFYYI NPKQLEFILN KLKQTNNTQL SKNKLHWVSY 600
DYYLALYE 608 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR016181; Acyl_CoA_acyltransferase.
 IPR000953; Chromo_domain/shadow.
 IPR016197; Chromodomain-like.
 IPR002717; MOZ_SAS.
 IPR025995; Tudor-knot.
 IPR015880; Znf_C2H2-like. 
Pfam
 PF01853; MOZ_SAS
 PF11717; Tudor-knot 
SMART
 SM00298; CHROMO
 SM00355; ZnF_C2H2 
PROSITE
  
PRINTS