Tag | Content |
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CPLM ID | CPLM-016955 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Palmitoyltransferase ZDHHC13 |
Protein Synonyms/Alias | Huntingtin-interacting protein 14-related protein; HIP14-related protein; Huntingtin-interacting protein HIP3RP; Putative MAPK-activating protein PM03; Putative NF-kappa-B-activating protein 209; Zinc finger DHHC domain-containing protein 13; DHHC-13 |
Gene Name | ZDHHC13 |
Gene Synonyms/Alias | HIP14L; HIP3RP |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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38 | PSLNVVDKIHQNTPL | ubiquitination | [1] | 73 | SLDIQNVKGETPLDM | ubiquitination | [1] |
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Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | Palmitoyltransferase for HD and GAD2 (By similarity). Mediates Mg(2+) transport (By similarity). |
Sequence Annotation | REPEAT 81 110 ANK 1. REPEAT 115 144 ANK 2. REPEAT 148 177 ANK 3. REPEAT 181 211 ANK 4. REPEAT 216 245 ANK 5. REPEAT 249 277 ANK 6. ZN_FING 426 476 DHHC-type. ACT_SITE 456 456 S-palmitoyl cysteine intermediate (By |
Keyword | Acyltransferase; Alternative splicing; ANK repeat; Complete proteome; Cytoplasmic vesicle; Golgi apparatus; Ion transport; Lipoprotein; Magnesium; Membrane; Metal-binding; Palmitate; Polymorphism; Reference proteome; Repeat; Transferase; Transmembrane; Transmembrane helix; Transport; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 622 AA |
Protein Sequence | MTDVNGQTPL MLSAHKVIGP EPTGFLLKFN PSLNVVDKIH QNTPLHWAVA AGNVNAVDKL 60 LEAGSSLDIQ NVKGETPLDM ALQNKNQLII HMLKTEAKMR ANQKFRLWRW LQKCELFLLL 120 MLSVITMWAI GYILDFNSDS WLLKGCLLVT LFFLTSLFPR FLVGYKNLVY LPTAFLLSSV 180 FWIFMTWFIL FFPDLAGAPF YFSFIFSIVA FLYFFYKTWA TDPGFTKASE EEKKVNIITL 240 AETGSLDFRT FCTSCLIRKP LRSLHCHVCN CCVARYDQHC LWTGRCIGFG NHHYYIFFLF 300 FLSMVCGWII YGSFIYLSSH CATTFKEDGL WTYLNQIVAC SPWVLYILML ATFHFSWSTF 360 LLLNQLFQIA FLGLTSHERI SLQKQSKHMK QTLSLRKTPY NLGFMQNLAD FFQCGCFGLV 420 KPCVVDWTSQ YTMVFHPARE KVLRSV 446 |
Gene Ontology | GO:0030660; C:Golgi-associated vesicle membrane; ISS:UniProtKB. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0015095; F:magnesium ion transmembrane transporter activity; ISS:UniProtKB. GO:0016409; F:palmitoyltransferase activity; ISS:UniProtKB. GO:0004871; F:signal transducer activity; IMP:UniProtKB. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB. |
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