CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007513
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 NADPH dehydrogenase 3 
Protein Synonyms/Alias
 Old yellow enzyme 3 
Gene Name
 OYE3 
Gene Synonyms/Alias
 YPL171C; P2291 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
369EEGLPLNKYDRSTFYubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Oxidizes beta-NADH, beta-NADPH, and alpha-NADPH. 
Sequence Annotation
 ACT_SITE 197 197 Proton donor (By similarity).
 BINDING 38 38 FMN (By similarity).
 BINDING 192 192 FMN (By similarity).
 BINDING 192 192 Substrate (By similarity).
 BINDING 195 195 Substrate (By similarity).
 BINDING 244 244 FMN (By similarity).
 BINDING 349 349 FMN (By similarity).
 BINDING 376 376 Substrate (By similarity).  
Keyword
 Complete proteome; Flavoprotein; FMN; NADP; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 400 AA 
Protein Sequence
MPFVKGFEPI SLRDTNLFEP IKIGNTQLAH RAVMPPLTRM RATHPGNIPN KEWAAVYYGQ 60
RAQRPGTMII TEGTFISPQA GGYDNAPGIW SDEQVAEWKN IFLAIHDCQS FAWVQLWSLG 120
WASFPDVLAR DGLRYDCASD RVYMNATLQE KAKDANNLEH SLTKDDIKQY IKDYIHAAKN 180
SIAAGADGVE IHSANGYLLN QFLDPHSNKR TDEYGGTIEN RARFTLEVVD ALIETIGPER 240
VGLRLSPYGT FNSMSGGAEP GIIAQYSYVL GELEKRAKAG KRLAFVHLVE PRVTDPSLVE 300
GEGEYSEGTN DFAYSIWKGP IIRAGNYALH PEVVREQVKD PRTLIGYGRF FISNPDLVYR 360
LEEGLPLNKY DRSTFYTMSA EGYTDYPTYE EAVDLGWNKN 400 
Gene Ontology
 GO:0010181; F:FMN binding; IEA:InterPro.
 GO:0003959; F:NADPH dehydrogenase activity; IDA:SGD.
 GO:0018548; F:pentaerythritol trinitrate reductase activity; IEA:EC.
 GO:0052690; F:trichloro-p-hydroquinone reductive dehalogenase activity; IEA:EC.
 GO:0006915; P:apoptotic process; IMP:SGD. 
Interpro
 IPR013785; Aldolase_TIM.
 IPR001155; OxRdtase_FMN_N. 
Pfam
 PF00724; Oxidored_FMN 
SMART
  
PROSITE
  
PRINTS