| Tag | Content |
|---|
| CPLM ID | CPLM-012893 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Echinoderm microtubule-associated protein-like 3 |
Protein Synonyms/Alias | EMAP-3 |
Gene Name | EML3 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 173 | PRQKLSRKAISSANL | ubiquitination | [1] | | 193 | STESRGGKDPLSSPG | ubiquitination | [1] | | 577 | ELLVGTTKNALLRGD | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity). |
Sequence Annotation | REPEAT 303 352 WD 1.
REPEAT 357 400 WD 2.
REPEAT 403 442 WD 3.
REPEAT 457 495 WD 4.
REPEAT 512 551 WD 5.
REPEAT 595 634 WD 6.
REPEAT 678 717 WD 7.
REPEAT 724 763 WD 8.
REPEAT 837 877 WD 9.
MOD_RES 176 176 Phosphoserine.
MOD_RES 881 881 Phosphothreonine. |
Keyword | Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Phosphoprotein; Polymorphism; Reference proteome; Repeat; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 896 AA |
Protein Sequence | MDGAAGPGDG PAREALQSLS QRLRVQEQEM ELVKAALAEA LRLLRLQVPP SSLQGSGTPA 60
PPGDSLAAPP GLPPTCTPSL VSRGTQTETE VELKSSPGPP GLSNGPPAPQ GASEEPSGTQ 120
SEGGGSSSSG AGSPGPPGIL RPLQPPQRAD TPRRNSSSSS SPSERPRQKL SRKAISSANL 180
LVRSGSTESR GGKDPLSSPG GPGSRRSNYN LEGISVKMFL RGRPITMYIP SGIRSLEELP 240
SGPPPETLSL DWVYGYRGRD SRSNLFVLRS GEVVYFIACV VVLYRPGGGP GGPGGGGQRH 300
YRGHTDCVRC LAVHPDGVRV ASGQTAGVDK DGKPLQPVVH IWDSETLLKL QEIGLGAFER 360
GVGALAFSAA DQGAFLCVVD DSNEHMLSVW DCSRGMKLAE IKSTNDSVLA VGFNPRDSSC 420
IVTSGKSHVH FWNWSGGVGV PGNGTLTRKQ GVFGKYKKPK FIPCFVFLPD GDILTGDSEG 480
NILTWGRSPS DSKTPGRGGA KETYGIVAQA HAHEGSIFAL CLRRDGTVLS GGGRDRRLVQ 540
WGPGLVALQE AEIPEHFGAV RAIAEGLGSE LLVGTTKNAL LRGDLAQGFS PVIQGHTDEL 600
WGLCTHPSQN RFLTCGHDRQ LCLWDGESHA LAWSIDLKET GLCADFHPSG AVVAVGLNTG 660
RWLVLDTETR EIVSDVIDGN EQLSVVRYSP DGLYLAIGSH DNVIYIYSVS SDGAKSSRFG 720
RCMGHSSFIT HLDWSKDGNF IMSNSGDYEI LYWDVAGGCK QLKNRYESRD REWATYTCVL 780
GFHVYVPVRS CQGAEPHVRG PRQPRDQRPI HARRLAPRLA GRQGRQHLPV ASAGRWGRGA 840
GARHALSNPL PVPRLLPRRL IAAWRDRLAR RRGPAPPCPS LAQSPTTRGR LFPGLTSRHS 900
RSRIFLEGAN GAPAHTV 917 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |