CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028291
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sperm surface protein Sp17 
Protein Synonyms/Alias
 Sperm autoantigenic protein 17 
Gene Name
 Spa17 
Gene Synonyms/Alias
 sp17; rCG_58879 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
63DPAEWGAKVEDRFYNacetylation[1]
75FYNNHAFKDPEQAEKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
 Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 148 AA 
Protein Sequence
MSIPFSNTHY RIPQGFGNLL EGLTREILRE QPDNIPAFAA AYFENLLEKR EKTSFDPAEW 60
GAKVEDRFYN NHAFKDPEQA EKCEQEIAKA SGREETPVTP FEESTEEERE QEEAAVKIQS 120
AFRGHVAREE VKKMKSDKSE NVKEEENN 148 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0031514; C:motile cilium; IEA:Compara.
 GO:0072372; C:primary cilium; IEA:Compara.
 GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.
 GO:0007339; P:binding of sperm to zona pellucida; IEA:InterPro.
 GO:0001539; P:ciliary or flagellar motility; IEA:Compara.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR003117; cAMP_dep_PK_reg_su_I/II_a/b.
 IPR000048; IQ_motif_EF-hand-BS.
 IPR012105; Sp17. 
Pfam
 PF00612; IQ
 PF02197; RIIa 
SMART
 SM00015; IQ
 SM00394; RIIa 
PROSITE
 PS50096; IQ 
PRINTS