| Tag | Content |
|---|
| CPLM ID | CPLM-011166 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | E3 SUMO-protein ligase SIZ1 |
Protein Synonyms/Alias | SAP and Miz-finger domain-containing protein 1; Ubiquitin-like protein ligase 1 |
Gene Name | SIZ1 |
Gene Synonyms/Alias | ULL1; YDR409W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 213 | SAKFKLSKADYNLLS | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Acts as an E3 ligase mediating SUMO/Smt3 attachment to septins and PCNA. May be involved in chromosome maintenance. |
Sequence Annotation | DOMAIN 34 68 SAP.
DOMAIN 162 314 PINIT.
ZN_FING 346 423 SP-RING-type.
REGION 794 904 Required for localization at the bud
MOD_RES 132 132 Phosphoserine.
MOD_RES 794 794 Phosphoserine. |
Keyword | 3D-structure; Complete proteome; Cytoplasm; Ligase; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Ubl conjugation; Ubl conjugation pathway; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 904 AA |
Protein Sequence | MINLEDYWED ETPGPDREPT NELRNEVEET ITLMELLKVS ELKDICRSVS FPVSGRKAVL 60
QDLIRNFLQN ALVVGKSDPY RVQAVKFLIE RIRKNEPLPV YKDLWNALRK GTPLSAITVR 120
SMEGPPTVQQ QSPSVIRQSP TQRRKTSTTS STSRAPPPTN PDASSSSSSF AVPTIHFKES 180
PFYKIQRLIP ELVMNVEVTG GRGMCSAKFK LSKADYNLLS NPNSKHRLYL FSGMINPLGS 240
RGNEPIQFPF PNELRCNNVQ IKDNIRGFKS KPGTAKPADL TPHLKPYTQQ NNVELIYAFT 300
TKEYKLFGYI VEMITPEQLL EKVLQHPKII KQATLLYLKK TLREDEEMGL TTTSTIMSLQ 360
CPISYTRMKY PSKSINCKHL QCFDALWFLH SQLQIPTWQC PVCQIDIALE NLAISEFVDD 420
ILQNCQKNVE QVELTSDGKW TAILEDDDDS DSDSNDGSRS PEKGTSVSDH HCSSSHPSEP 480
IIINLDSDDD EPNGNNPHVT NNHDDSNRHS NDNNNNSIKN NDSHNKNNNN NNNNNNNNND 540
NNNSIENNDS NSNNKHDHGS RSNTPSHNHT KNLMNDNDDD DDDRLMAEIT SNHLKSTNTD 600
ILTEKGSSAP SRTLDPKSYN IVASETTTPV TNRVIPEYLG NSSSYIGKQL PNILGKTPLN 660
VTAVDNSSHL ISPDVSVSSP TPRNTASNAS SSALSTPPLI RMSSLDPRGS TVPDKTIRPP 720
INSNSYTASI SDSFVQPQES SVFPPREQNM DMSFPSTVNS RFNDPRLNTT RFPDSTLRGA 780
TILSNNGLDQ RNNSLPTTEA ITRNDVGRQN STPVLPTLPQ NVPIRTNSNK SGLPLINNEN 840
SVPNPPNTAT IPLQKSRLIV NPFIPRRPYS NVLPQKRQLS NTSSTSPIMG TWKTQDYGKK 900
YNSG 904 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |