CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-040057
UniProt Accession
F5H877_HUMAN
;
F5H877
Genbank Protein ID
AC012476
Genbank Nucleotide ID
Protein Name
Kunitz-type protease inhibitor 1
Protein Synonyms/Alias
Gene Name
SPINT1
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Homo sapiens (Human)
NCBI Taxa ID
9606
Lysine Modification
Position
Peptide
Type
References
139
AWAGIDL
K
VQPQEPL
ubiquitination
[1]
Reference
[1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
Mol Cell. 2011 Oct 21;44(2):325-40. [
PMID: 21906983
]
Functional Description
Sequence Annotation
Keyword
Complete proteome; Disulfide bond; Reference proteome.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
496 AA
Protein Sequence
MAPARTMARA RLAPADCLNS FTAGVPGFVL DTNASVSNGA TFLESPTVRR GWDCVRACCT 60
TQNCNLALVE LQPDRGEDAI AACFLINCLY EQNFVCKFAP REGFINYLTR EVYRSYRQLR 120
TQGFGGSGIP KAWAGIDLKV QPQEPLVLKD VENTDWRLLR GDTDVRVERK DPNQVELWGL 180
KEGTYLFQLT VTSSDHPEDT ANVTVTVLST KQTEDYCLAS NKVGRCRGSF PRWYYDPTEQ 240
ICKSFVYGGC LGNKNNYLRE EECILACRGV QGGPLRGSSG AQATFPQGPS MERRHPVCSG 300
TCQPTQFRCS NGCCIDSFLE CDDTPNCPDA SDEAACEKYT SGFDELQRIH FPSDKGHCVD 360
LPDTGLCKES IPRWYYNPFS EHCARFTYGG CYGNKNNFEE EQQCLESCRG ISKKDVFGLR 420
REIPIPSTGS VEMAVAVFLV ICIVVVVAIL GYCFFKNQRK DFHGHHHHPP PTPASSTVST 480
TEDTEHLVYN HTTRPL 496
Gene Ontology
GO:0004867
; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
Interpro
IPR023415
; LDLR_class-A_CS.
IPR002172
; LDrepeatLR_classA_rpt.
IPR013980
; MANSC.
IPR011106
; MANSC_N.
IPR002223
; Prot_inh_Kunz-m.
IPR020901
; Prtase_inh_Kunz-CS.
Pfam
PF00014
; Kunitz_BPTI
PF00057
; Ldl_recept_a
PF07502
; MANEC
SMART
SM00131
; KU
SM00192
; LDLa
SM00765
; MANEC
PROSITE
PS00280
; BPTI_KUNITZ_1
PS50279
; BPTI_KUNITZ_2
PS01209
; LDLRA_1
PS50068
; LDLRA_2
PS50986
; MANSC
PRINTS
PR00759
; BASICPTASE.