UniProt Accession

 GTS1_YEAST; P40956; D6VTX2 

Genbank Protein ID

 D31853; X85806; X91489; Z72703; BK006941 

Genbank Nucleotide ID

 BAA06637.1; CAA59801.1; CAA62793.1; CAA96893.1; DAA07933.1 

Protein Name

 Protein GTS1 

Protein Synonyms/Alias

 Protein LSR1 

Gene Name

 GTS1 

Gene Synonyms/Alias

 LSR1; YGL181W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
18	KHVDRELKELINSSE	ubiquitination	[1]
95	LVSLGGNKGNARFWN	ubiquitination	[1]
233	RAIDYLEKSSSSRNS	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Appears to modulate the timing of budding to obtain an appropriate cell size independent of the DNA replication cycle. Transcription factor involved in both heat resistance and flocculation. 

Sequence Annotation

 DOMAIN 14 141 Arf-GAP.
 DOMAIN 193 234 UBA.
 ZN_FING 30 53 C4-type.
 MOD_RES 153 153 Phosphoserine.
 MOD_RES 181 181 Phosphotyrosine.
 MOD_RES 184 184 Phosphoserine.
 MOD_RES 187 187 Phosphoserine.
 MOD_RES 240 240 Phosphoserine.
 MOD_RES 249 249 Phosphothreonine.  

Keyword

 Complete proteome; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 396 AA 

Protein Sequence

Gene Ontology

 GO:0030479; C:actin cortical patch; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0008060; F:ARF GTPase activator activity; IMP:SGD.
 GO:0000989; F:transcription factor binding transcription factor activity; IMP:SGD.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006897; P:endocytosis; IMP:SGD.
 GO:0010512; P:negative regulation of phosphatidylinositol biosynthetic process; IMP:SGD.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.
 GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0007624; P:ultradian rhythm; IMP:SGD. 

Interpro

 IPR001164; ArfGAP.
 IPR009060; UBA-like.
 IPR000449; UBA/transl_elong_EF1B_N.
 IPR015940; UBA/transl_elong_EF1B_N_euk. 

Pfam

 PF01412; ArfGap
 PF00627; UBA 

SMART

 SM00105; ArfGap
 SM00165; UBA 

PROSITE

 PS50115; ARFGAP
 PS50030; UBA 

PRINTS

 PR00405; REVINTRACTNG.