UniProt Accession

 CLCB_HUMAN; P09497; Q53Y37; Q6FHW1 

Genbank Protein ID

 M20469; M20470; BT007028; CR536577; CH471195; BC006332; BC006457 

Genbank Nucleotide ID

 AAA51818.1; AAA59506.1; AAP35675.1; CAG38814.1; EAW85079.1; AAH06332.1; AAH06457.1 

Protein Name

 Clathrin light chain B 

Protein Synonyms/Alias

 Lcb 

Gene Name

 CLTB 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
223	RSVLMSLKQTPLSR*	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

 Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. 

Sequence Annotation

 REGION 93 155 Involved in binding clathrin heavy chain.
 MOD_RES 11 11 Phosphoserine (By similarity).
 MOD_RES 13 13 Phosphoserine (By similarity).
 DISULFID 199 209 By similarity.  

Keyword

 Alternative splicing; Calcium; Coated pit; Complete proteome; Cytoplasmic vesicle; Disulfide bond; Membrane; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 229 AA 

Protein Sequence

Gene Ontology

 GO:0060170; C:cilium membrane; IEA:Compara.
 GO:0030118; C:clathrin coat; ISS:UniProtKB.
 GO:0030132; C:clathrin coat of coated pit; IEA:InterPro.
 GO:0030130; C:clathrin coat of trans-Golgi network vesicle; IEA:InterPro.
 GO:0005802; C:trans-Golgi network; IEA:Compara.
 GO:0042277; F:peptide binding; IEA:Compara.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; NAS:UniProtKB.
 GO:0016192; P:vesicle-mediated transport; IEA:InterPro. 

Interpro

 IPR000996; Clathrin_L-chain. 

Pfam

 PF01086; Clathrin_lg_ch 

SMART

  

PROSITE

 PS00224; CLATHRIN_LIGHT_CHN_1
 PS00581; CLATHRIN_LIGHT_CHN_2 

PRINTS