CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001091
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Reticulon-2 
Protein Synonyms/Alias
 Neuroendocrine-specific protein-like 1; NSP-like protein 1; Neuroendocrine-specific protein-like I; NSP-like protein I; NSPLI 
Gene Name
 Rtn2 
Gene Synonyms/Alias
 Nspl1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
279VADLLYWKDTRTSGAubiquitination[1]
450IKAKIRAKIPGTGTLubiquitination[1]
467TASVSGSKAKAE***ubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
 DOMAIN 272 471 Reticulon.
 MOD_RES 44 44 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Endoplasmic reticulum; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 471 AA 
Protein Sequence
MGQVLPVFAH CKEAPSTASS TPDSTEGGND DSDFRELHTA REFSEDEEEE TTSQDWGTPR 60
ELTFSYIAFD GVVGSGGRRD SVVRRPRPQG RSVSEPRDPP QQSGLGDSLE SIPSLSQSPE 120
PGRRGDPDPV PPAERPLEEL RLRLDQLGWV VRSAGSGEDS ATSSSTPLEN EEPDGLEASE 180
AGEETNLELR LAQSLHLQLE VLTPQLSPSS GTPQAHTPSP QRSQDSNSGP DDEPLLNVVE 240
EHWRLLEQEP ITAQCLDSTD QSEFMLEPLL LVADLLYWKD TRTSGAVFTG LMASLLCLLH 300
FSIVSVAAHL ALLGLCATIS LRVYRKVLQA VHRGDGTNPF QAYLDMDLTL TREQTERLSQ 360
QIASHVVSTA TQLRHFFLVE DLVDSLKLAL LFYILTFVGA IFNGLTLVIL GVVALFTVPL 420
LYRQHQAQID QYVGLVTNQL SHIKAKIRAK IPGTGTLAPT ASVSGSKAKA E 471 
Gene Ontology
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR003388; Reticulon. 
Pfam
 PF02453; Reticulon 
SMART
  
PROSITE
 PS50845; RETICULON 
PRINTS