CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036440
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Elongation factor G, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 Gfm1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
176PFLTFINKLDRMGSNacetylation[1]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 560 AA 
Protein Sequence
MRLLRVAAAL GRGPFPRVPA VLGWQGKQAD WKTRRWCSSG PVPNEKIRNI GISAHIDSGK 60
TTLTERVLYY TGRIATMHEV KGKDGVGAVM DSMELERQRG ITIQSAATYT MWKDININII 120
DTPGHVDFTI EVERALRVLD GAVLVLCAVG GVQCQTMTVS RQMKRYNVPF LTFINKLDRM 180
GSNPSRALQQ MRSKLNHNAA FVQIPIGLEG DFKGIIDLIE ERAIYFDGDF GQIVRYDEIP 240
AGLRAAAADH RQELIECVAN SDEQLGELFL EEKIPSVSDL KRAIRRATLS RSFTPVFLGS 300
ALKNKGVQPL LDAVLEYLPN PSEVQNYAIL NQNDSKEKTK ILMNPQRDDS HPFVGLAFKL 360
EAGRFGQLTY VRNYQGELKK GSTIYNTRTG KKVRVQRLVR MHADMMEDVE EVYAGDICAL 420
FGIDCASGDT FTNKDNSDLS MESIHVPEPV ISIAMRPSNK NDLEKFSKGI GRFTREDPTF 480
KVHFDPESKE TIVSGMGELH LEIYAQRMER EYGCPCITGK PKVAFRETIV APVPVASNKE 540
KLYMLPAMQC RGVEWCNLTQ 560 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0006184; P:GTP catabolic process; IEA:GOC. 
Interpro
 IPR000795; EF_GTP-bd_dom.
 IPR009022; EFG_III-V.
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR004161; Transl_elong_EFTu/EF1A_2.
 IPR009000; Transl_elong_init/rib_B-barrel. 
Pfam
 PF00009; GTP_EFTU
 PF03144; GTP_EFTU_D2 
SMART
  
PROSITE
 PS00301; EFACTOR_GTP 
PRINTS
 PR00315; ELONGATNFCT.