CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002857
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glutamine synthetase 
Protein Synonyms/Alias
 Glutamate--ammonia ligase 
Gene Name
 glnA 
Gene Synonyms/Alias
 STM4007 
Created Date
 July 27, 2013 
Organism
 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 
NCBI Taxa ID
 99287 
Lysine Modification
Position
Peptide
Type
References
164GAWNSSTKYEGGNKGacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
  
Sequence Annotation
 MOD_RES 398 398 O-AMP-tyrosine (By similarity).  
Keyword
 3D-structure; ATP-binding; Complete proteome; Cytoplasm; Ligase; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 469 AA 
Protein Sequence
MSAEHVLTML NEHEVKFVDL RFTDTKGKEQ HVTIPAHQVN AEFFEEGKMF DGSSIGGWKG 60
INESDMVLMP DASTAVIDPF FADSTLIIRC DILEPGTLQG YDRDPRSIAK RAEDYLRATG 120
IADTVLFGPE PEFFLFDDIR FGASISGSHV AIDDIEGAWN SSTKYEGGNK GHRPGVKGGY 180
FPVPPVDSAQ DIRSEMCLVM EQMGLVVEAH HHEVATAGQN EVATRFNTMT KKADEIQIYK 240
YVVHNVAHRF GKTATFMPKP MFGDNGSGMH CHMSLAKNGT NLFSGDKYAG LSEQALYYIG 300
GVIKHAKAIN ALANPTTNSY KRLVPGYEAP VMLAYSARNR SASIRIPVVA SPKARRIEVR 360
FPDPAANPYL CFAALLMAGL DGIKNKIHPG EAMDKNLYDL PPEEAKEIPQ VAGSLEEALN 420
ALDLDREFLK AGGVFTDEAI DAYIALRREE DDRVRMTPHP VEFELYYSV 469 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004356; F:glutamate-ammonia ligase activity; IEA:EC.
 GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
 GO:0009399; P:nitrogen fixation; IEA:InterPro. 
Interpro
 IPR008147; Gln_synt_beta.
 IPR014746; Gln_synth/guanido_kin_cat_dom.
 IPR008146; Gln_synth_cat_dom.
 IPR027303; Gln_synth_gly_rich_site.
 IPR004809; Gln_synth_I.
 IPR001637; Gln_synth_I_adenylation_site.
 IPR027302; Gln_synth_N_conserv_site. 
Pfam
 PF00120; Gln-synt_C
 PF03951; Gln-synt_N 
SMART
  
PROSITE
 PS00180; GLNA_1
 PS00182; GLNA_ADENYLATION
 PS00181; GLNA_ATP 
PRINTS