CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034046
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 YLP motif-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 Ylpm1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
322KKGLVTAKDVPEPIKacetylation[1]
510TQTYLQEKVNSFQTVubiquitination[2]
730SQSIIAAKDTPVKSGacetylation[1, 3]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2139 AA 
Protein Sequence
MYPNWGRYGG SSHYPPPPVP PPPPPVALPE ASPGPGYSSS TAPAAPSSSG FMSFREQHLA 60
QLQQLQQMHQ KQMQCVLQPH HLPPPPLPPP PVMPGGGYGD WQPPPPPMPP PPGPALSYQK 120
QQQYKHQMIH HQRDGPPGLV PMELESPPES PPVPPGSYMP PSQSYMPPPQ PPPSYYPPSS 180
AQPYLPPAQP SPSQSPPSQS YLAPTPSYSS SSSSQSYLSH SQPYLPPSQA SPSRSSQGPS 240
KPQLPPPPSI PSGNKTAIQQ EPLESGAKNK TAEQKQAAPE PDPSTMTPQE QQQYWYRQHL 300
LSLQQRTKVH LPGHKKGLVT AKDVPEPIKE EAPGPAASQV AEPLAAEKPP LPPPNEEAPP 360
PLSPEEPQSE DSEDSEDSEE DARFKQLKAI AAHWQAAAAH WQQQQQQRVG FQYQGIMQRH 420
TQLQQILQQY QQVIQHSPHI QTMSLDVQLR HYEMQQQQFQ HLFQDWEREF QLWEEQLHSY 480
PHKDQLQEYE KQWKTWQGHM KATQTYLQEK VNSFQTVKSQ YLGNMAMPPP FVPYSQMPPP 540
LPTMPPPVLP PSLPPPVMPP ALPTSIPPPG MPPPVMPPSL PTSVPPPGMP PSLSSGPPPV 600
LPPPALSSAG SPPVLPPPAL PGGPPILPLP PLSSATPPPG IPPPGAPQGM PPQLTAPLPP 660
ASGSQNSQIP EKPRQALLPT PVSFGSTPPS PYHPPPQSEQ VNSKPLNKVF SSEQGLGESS 720
ALSQSIIAAK DTPVKSGGLL ADPPKGSFLE GPRGPRFDGP RRFEDLGSRC EGPRPKGPRF 780
EGNRPDGPRP RYESHPAEGT KSKWGTIPRG PASQFYITPN TSLSPRQSGP QWKGPKATVG 840
QQHQQQPKQQ PKSQAEPLSG NKEPLADTSN NQQKNLKIQS AAFSISADVK DTKAAQSNEN 900
LSDSQQEPTK SQVSEGPVEP SNWNQNSQSM ETEMDKAEGV TQPVSLANKP VPTQSTFPSK 960
VGSMEGGAAA AALTADDFKP LGVGLSHSEN HQEKDLPQPD SRENRLEGNK GSSSSYRGPG 1020
QNRVEESRDK GLVNRGRGQI INRGPGLVKQ EDFHDKMMGR REDSREKMNR GEGNRDRVFV 1080
RPGSSRDKIP GGLQDSQDSR ANSRERGPPR RAGSQERGPP RRAGSRERVP PQRAGSRERV 1140
PPRGPGSRER GLGRPDFGHD RVPFRSELGD GGDKVYPYHR DEPSRASWNH GEERGHEEFP 1200
VDGRNAPIER ERLDDWDRKR YWRECERDYQ DDTLDSYSRE DRFSAPPSRS HDGDRRGPWW 1260
DDWERDQDMD EGYGREMDRD LDRDVDRIRR PLDIYDRNVD NEWDRDYGRP LDEQESQFRE 1320
RDIPSLPPLP PLPPLPPLDR YRDDRWREER NRDHGYDRDF RDRGELRIRE YPERGDTWRE 1380
KRDYVPDRMD WERERLSDRW YPSDVDRHSP MAEHMPSSHH SSEMMGSDAN LDSDQGLGGV 1440
MVLSQRQHEI ILKAAQELKM LREQKEQLQK LKDFGSEPQM ADHLPPPDSR LQNPSRPGMY 1500
PPPGSYRPPP PMGKPPGSIV RPSAPPARSS IPMTRPPVPI PPPPPPPPPP PPPPPVIKSK 1560
TSSVKQERWD EDSFFGLWDT NDDQGLNSEF KRDTATIPSA PVLPPPPVHS SIPPPGPMPM 1620
GMPPMSKPPP VQHTVDYGHG RDMPTNKVEQ IPYGERITLR PDPLPERSTF DADHAGQRDR 1680
YDRDRDREPY FDRPSNITDH RDFKRDRETH RDRDRDRVLD YERDRFDRER RPRDDRNQSY 1740
RDKKDHSSSR RGGFDRPSYD RKSDRPPYEG PPMFGGERRT YPEERMPLPA PALGHQPPPV 1800
PRVEKKPESK NVDDILKPPG RESRPERIVV IMRGLPGSGK THVAKLIRDK EVEFGGPAPR 1860
VLSLDDYFIA EVEKEEKDPD SGKKVKKKVM EYEYEADMEE TYRTSMFKTF KKTLDDGFFP 1920
FIILDAINDR VRHFDQFWSA AKTKGFEVYL AEMSADNQTC GKRNIHGRKL KEINKMAEHW 1980
EVAPRHMMRL DIRSLLQDAA IEEVEMEDFD ANIEDQKEEK KDAEEEESEL GYIPKSKWEM 2040
DTSEAKLDKL DGLRTGTKRK RDWEAIASRM EDYLQLPDDY ETRASEPGKK RVRWADLEEK 2100
KDADRKRAIG FVVGQTDWEK ITDESGHLAE RALNRTKYI 2139 
Gene Ontology
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:MGI.
 GO:0032204; P:regulation of telomere maintenance; IDA:MGI. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR026314; YLP_motif_con_p1. 
Pfam
  
SMART
  
PROSITE
  
PRINTS