CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026102
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Galactokinase 1 
Protein Synonyms/Alias
 Galactokinase 1, isoform CRA_c; Protein Galk1 
Gene Name
 Galk1 
Gene Synonyms/Alias
 rCG_35086 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
301ALSRGDYKAFGRLMVacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 392 AA 
Protein Sequence
MAAWRPPRVE ELLAEARRAF MEEFGAEPEL AVSAPGRVNL IGEHTDYNQG LVLPMALELV 60
TVMVGSPRTD GLVSLLTTSK DADEPQRLQF PLPSAQWSLE PGIPQWANYV KGVIQYYPAS 120
PLCGFSAVVV SSVPLGGGLS SSASLEVATY AFLQQLCPDS GSIAARAQVC QRAEHSFAGV 180
PCGIMDQLIA LLGQKGYALL IDCRSLETSL VPLSDPKLTV LITNSNVRHS LASSEYPIRR 240
RQCEEVAQAL GKESLREVRM EELEAGRELM SKEGFRRARH VVSEIRRTAQ GAAALSRGDY 300
KAFGRLMVES HYSLRDDYEV SCPELDLLVE AALSVPGVYG SRMTGGGFGG CTVTLLEASV 360
APLVMHHIQE QYSGTATFYL TQAADGAQVL SL 392 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005524; F:ATP binding; IMP:RGD.
 GO:0004335; F:galactokinase activity; IDA:RGD.
 GO:0005534; F:galactose binding; IDA:RGD.
 GO:0019402; P:galactitol metabolic process; IEA:Compara.
 GO:0006012; P:galactose metabolic process; IDA:RGD. 
Interpro
 IPR000705; Galactokinase.
 IPR019741; Galactokinase_CS.
 IPR019539; GalKase_gal-bd.
 IPR013750; GHMP_kinase_C_dom.
 IPR006204; GHMP_kinase_N_dom.
 IPR006203; GHMP_knse_ATP-bd_CS.
 IPR006206; Mevalonate/galactokinase.
 IPR020568; Ribosomal_S5_D2-typ_fold.
 IPR014721; Ribosomal_S5_D2-typ_fold_subgr. 
Pfam
 PF10509; GalKase_gal_bdg
 PF08544; GHMP_kinases_C
 PF00288; GHMP_kinases_N 
SMART
  
PROSITE
 PS00106; GALACTOKINASE
 PS00627; GHMP_KINASES_ATP 
PRINTS
 PR00473; GALCTOKINASE.
 PR00959; MEVGALKINASE.