CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017656
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Metal transporter CNNM3 
Protein Synonyms/Alias
 Ancient conserved domain-containing protein 3; Cyclin-M3 
Gene Name
 CNNM3 
Gene Synonyms/Alias
 ACDP3 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
306DPYSDLSKGVLRCRTubiquitination[1]
441KVSDDEYKVTISPQLubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
 Probable metal transporter (By similarity). 
Sequence Annotation
 DOMAIN 137 288 DUF21.
 DOMAIN 318 379 CBS 1.
 DOMAIN 386 452 CBS 2.
 MOD_RES 661 661 Phosphoserine.
 MOD_RES 700 700 Phosphoserine (By similarity).
 CARBOHYD 73 73 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; CBS domain; Cell membrane; Complete proteome; Glycoprotein; Ion transport; Membrane; Phosphoprotein; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 707 AA 
Protein Sequence
MAAAVAAAGR LGWLFAALCL GNAAGEAAPG PRVLGFCLEE DGAAGAGWVR GGAARDTPDA 60
TFLLRLFGPG FANSSWSWVA PEGAGCREEA ASPAGEWRAL LRLRLRAEAV RPHSALLAVR 120
VEPGGGAAEE AAPPWALGLG AAGLLALAAL ARGLQLSALA LAPAEVQVLR ESGSEAERAA 180
ARRLEPARRW AGCALGALLL LASLAQAALA VLLYRAAGQR AVPAVLGSAG LVFLVGEVVP 240
AAVSGRWTLA LAPRALGLSR LAVLLTLPVA LPVGQLLELA ARPGRLRERV LELARGGGDP 300
YSDLSKGVLR CRTVEDVLTP LEDCFMLDAS TVLDFGVLAS IMQSGHTRIP VYEEERSNIV 360
DMLYLKDLAF VDPEDCTPLS TITRFYNHPL HFVFNDTKLD AVLEEFKRGD TVVKRKPASL 420
MAPLKRKEEF SLFKVSDDEY KVTISPQLLL ATQRFLSREV DVFSPLRISE KVLLHLLKHP 480
SVNQEVRFDE SNRLATHHYL YQRSQPVDYF ILILQGRVEV EIGKEGLKFE NGAFTYYGVS 540
ALTVPSSVHQ SPVSSLQPIR HDLQPDPGDG THSSAYCPDY TVRALSDLQL IKVTRLQYLN 600
ALLATRAQNL PQSPENTDLQ VIPGSQTRLL GEKTTTAAGS SHSRPGVPVE GSPGRNPGV 659 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0006811; P:ion transport; IEA:UniProtKB-KW. 
Interpro
 IPR000644; Cysta_beta_synth_core.
 IPR002550; DUF21. 
Pfam
 PF01595; DUF21 
SMART
  
PROSITE
 PS51371; CBS 
PRINTS