| Tag | Content |
|---|
| CPLM ID | CPLM-003101 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | ATP-dependent RNA helicase RhlB |
Protein Synonyms/Alias | |
Gene Name | rhlB |
Gene Synonyms/Alias | mmrA; b3780; JW3753 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 3 | *****MSKTHLTEQK | acetylation | [1] | | 10 | KTHLTEQKFSDFALH | acetylation | [1] | | 19 | SDFALHPKVVEALEK | acetylation | [1] | | 26 | KVVEALEKKGFHNCT | acetylation | [1] | | 126 | YGGDGYDKQLKVLES | acetylation | [1] | | 177 | MYDLGFIKDIRWLFR | acetylation | [1] | | 232 | QKTGHRIKEELFYPS | acetylation | [1] | | 266 | AIIFANTKHRCEEIW | acetylation | [1] | | 293 | LTGDVAQKKRLRILD | acetylation | [1] | | 395 | ALMTDLPKPLRLTRP | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Can carry out ATP-dependent unwinding of double stranded RNA. Has a role in RNA decay. Involved in the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation. |
Sequence Annotation | DOMAIN 40 219 Helicase ATP-binding.
DOMAIN 245 390 Helicase C-terminal.
NP_BIND 53 60 ATP (By similarity).
MOTIF 9 37 Q motif.
MOTIF 165 168 DEAD box. |
Keyword | ATP-binding; Complete proteome; Direct protein sequencing; Helicase; Hydrolase; Nucleotide-binding; Reference proteome; RNA-binding. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 421 AA |
Protein Sequence | MSKTHLTEQK FSDFALHPKV VEALEKKGFH NCTPIQALAL PLTLAGRDVA GQAQTGTGKT 60
MAFLTSTFHY LLSHPAIADR KVNQPRALIM APTRELAVQI HADAEPLAEA TGLKLGLAYG 120
GDGYDKQLKV LESGVDILIG TTGRLIDYAK QNHINLGAIQ VVVLDEADRM YDLGFIKDIR 180
WLFRRMPPAN QRLNMLFSAT LSYRVRELAF EQMNNAEYIE VEPEQKTGHR IKEELFYPSN 240
EEKMRLLQTL IEEEWPDRAI IFANTKHRCE EIWGHLAADG HRVGLLTGDV AQKKRLRILD 300
EFTRGDLDIL VATDVAARGL HIPAVTHVFN YDLPDDCEDY VHRIGRTGRA GASGHSISLA 360
CEEYALNLPA IETYIGHSIP VSKYNPDALM TDLPKPLRLT RPRTGNGPRR TGAPRNRRRS 420
G 421 |
Gene Ontology | GO:0005524; F:ATP binding; IEA:HAMAP. GO:0008026; F:ATP-dependent helicase activity; IDA:EcoCyc. GO:0004004; F:ATP-dependent RNA helicase activity; IEA:InterPro. GO:0003723; F:RNA binding; IEA:UniProtKB-KW. GO:0006401; P:RNA catabolic process; IDA:EcoCyc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |