CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007712
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MAP-homologous protein 1 
Protein Synonyms/Alias
  
Gene Name
 MHP1 
Gene Synonyms/Alias
 YJL042W; J1206 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
221VVPLTRSKTESEVYYubiquitination[1, 2]
526DDANAKSKEEMAPQKubiquitination[2]
1321EETAFRTKDEQQSSQubiquitination[2]
Reference
 [1] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Essential for the formation and/or stabilization of microtubules. Binds to microtubules in vitro. 
Sequence Annotation
 MOD_RES 81 81 Phosphoserine.
 MOD_RES 222 222 Phosphothreonine.
 MOD_RES 311 311 Phosphoserine.
 MOD_RES 354 354 Phosphoserine.
 MOD_RES 357 357 Phosphoserine.
 MOD_RES 577 577 Phosphothreonine.  
Keyword
 Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1398 AA 
Protein Sequence
MDSKDTQKLL KEHRIPCIDV GWLVRPSAST SKSSRPGKSE SKANSVAPDI QMDTARPPVF 60
ETSVDSSSSI LSSNDKGRRH SVAASLLMDN QRANAGSTSV PTNIPPPRGR SKSVVETNLS 120
NVEADSGHHH HHRHHHHTED APAPKKVGFF KSLFGHRKKD QEQQEKERER KERSPSPTHV 180
DRGAAIRRER TATISAESPP PLQYNAPPSY NDTVVPLTRS KTESEVYYEN HPQSYYHGRM 240
RTYHSPEEGK VDGTSPADDH NYGGSRPDPR LMDFLRYYKS KDYKLAAFKE GNFIKSSASP 300
TTKKNRRASF SLHNDKPQPA KSLAHQKFDA KGRPIPPHPD APKLPSAFRK KHPSNASIVD 360
TVDSNSDVSS SAQNNNQTPS SHKFGAFLRK VTSYGNNNNN STNASSLSAN VNNPDTSSTS 420
LWSSSSMEFD PSKITTVPGL ENIRPLKHVS FATNTYFNDP PQQICSKNPR KGEVEVKPNG 480
SVVIHRLTPQ ERKKIMESTS LGVVVGGTGQ LKLLNPEEDD ANAKSKEEMA PQKQNEVEAH 540
DEEDNNSQRR NIVMAAAEAA AEARAKEAPN ELKRIVTNNE EEVTVSKTAS HLTIDKPMIS 600
RRGASTSSLA SMVSSDTNGT NADDEGEILP PPSLKIPHDI VYTRCCHLRE ILPIPATLKQ 660
LKKGSTDPIP ILQLRNPRPS MVEIWSFSDF LSIAPVLCLS LDGVQLTVQM LRIILSSLVY 720
KQHFQKLSLR NTPLDEEGWK VLCYFVSKAK SLHSIDLTMV PSIKTNVQKP SKSSLKSKIL 780
RMQCNLENRS DMNWDLLTAS IALMGGLEEI VISGAKMNSA QFKNFILVAC IATERLGLAY 840
NGLSKSQCDD LAKWMVQSKV TGLDVGFNDL NGKLSSFTDA VLGKIQKANE KNVFKFLSLN 900
GTNLRVNEHD TFENNEVLKL ISVLCYLENL KFLDISNNPA IFPHCVPTLI DFLPVFVNLV 960
RLHIDYNNLS STSVVMLAEI LPMCSRLNYF SMLGTELDLA SSKALAEAVR KSSSLMTLDV 1020
DYVYMPENIK EKISLYALRN IQGELKRVNS DDKDIKDSQF SSLQDQLSLL LTEKADNSEH 1080
YNKMVENFMA KIALARIKIS KVVHDLFDLK LNGQLNLEGK EALIRLCFIE ASLERGCDLL 1140
KQRHNNTLKS PEAVSKSRKG GNQAQPNSES CQRMLLSSSI LQNSDHIALM PFGSAIVEKS 1200
SPDAEDAVEF REGDDSNVNH EDVPANDQQF RDEVDIKNKY SIIKRELEHE KLVGGGDLPV 1260
DKEILNRAAQ SLDSDQIKEF LLKNDVSTIL GVIDELHSQG YHLHHIFKKQ GNQEETAFRT 1320
KDEQQSSQSN DSSANASPTT DPISTGSNTS RTNDNAHIPP TDAPGFDKFM NNAEENAIDA 1380
AYDDVLDKIQ DARNSSTK 1398 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005874; C:microtubule; IDA:SGD.
 GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
 GO:0005200; F:structural constituent of cytoskeleton; IDA:SGD.
 GO:0031505; P:fungal-type cell wall organization; IMP:SGD.
 GO:0007026; P:negative regulation of microtubule depolymerization; IMP:SGD. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS