UniProt Accession

 CHP2_SCHPO; O42934 

Genbank Protein ID

 CU329671 

Genbank Nucleotide ID

 CAA16917.1 

Protein Name

 Chromo domain-containing protein 2 

Protein Synonyms/Alias

  

Gene Name

 chp2 

Gene Synonyms/Alias

 SPBC16C6.10 

Created Date

 July 27, 2013 

Organism

 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 

NCBI Taxa ID

 284812 

Lysine Modification

Position	Peptide	Type	References
198	SGFQYYLKWEGYDDP	sumoylation	[1]

Reference

 [1] SUMO modification is involved in the maintenance of heterochromatin stability in fission yeast.
 Shin JA, Choi ES, Kim HS, Ho JC, Watts FZ, Park SD, Jang YK.
 Mol Cell. 2005 Sep 16;19(6):817-28. [PMID: 16168376] 

Functional Description

 Component of the kinetochore which plays a role in stabilizing microtubules and so allowing accurate chromosome segregation. 

Sequence Annotation

 DOMAIN 176 238 Chromo.  

Keyword

 Complete proteome; DNA-binding; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 380 AA 

Protein Sequence

Gene Ontology

 GO:0005721; C:centromeric heterochromatin; TAS:PomBase.
 GO:0031934; C:mating-type region heterochromatin; TAS:PomBase.
 GO:0044732; C:mitotic spindle pole body; IDA:PomBase.
 GO:0005724; C:nuclear telomeric heterochromatin; TAS:PomBase.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0031493; F:nucleosomal histone binding; NAS:PomBase.
 GO:0006338; P:chromatin remodeling; NAS:PomBase.
 GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.
 GO:0000183; P:chromatin silencing at rDNA; IMP:PomBase.
 GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.
 GO:0006348; P:chromatin silencing at telomere; IMP:PomBase. 

Interpro

 IPR023780; Chromo_domain.
 IPR000953; Chromo_domain/shadow.
 IPR008251; Chromo_shadow_dom.
 IPR016197; Chromodomain-like. 

Pfam

 PF00385; Chromo
 PF01393; Chromo_shadow 

SMART

 SM00298; CHROMO
 SM00300; ChSh 

PROSITE

 PS00598; CHROMO_1
 PS50013; CHROMO_2 

PRINTS