UniProt Accession

 PCBP1_MOUSE; P60335 

Genbank Protein ID

 AF139894; AF139895; BC069915; BC004793 

Genbank Nucleotide ID

 AAD51920.1; AAD51921.1; AAH69915.1; AAH04793.1 

Protein Name

 Poly(rC)-binding protein 1 

Protein Synonyms/Alias

 Alpha-CP1; Heterogeneous nuclear ribonucleoprotein E1; hnRNP E1 

Gene Name

 Pcbp1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
115	QCGSLIGKGGCKIKE	acetylation	[1]
115	QCGSLIGKGGCKIKE	ubiquitination	[2]
237	ISPLDLAKLNQVARQ	ubiquitination	[2]
314	QMSGAQIKIANPVEG	ubiquitination	[2]

Reference

 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Single-stranded nucleic acid binding protein that binds preferentially to oligo dC (By similarity). 

Sequence Annotation

 DOMAIN 13 75 KH 1.
 DOMAIN 97 162 KH 2.
 DOMAIN 279 343 KH 3.
 MOD_RES 173 173 Phosphoserine.
 MOD_RES 190 190 Phosphoserine (By similarity).  

Keyword

 Complete proteome; Direct protein sequencing; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat; Ribonucleoprotein; RNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 356 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
 GO:0003723; F:RNA binding; TAS:MGI.
 GO:0003697; F:single-stranded DNA binding; IEA:Compara.
 GO:0008494; F:translation activator activity; TAS:MGI.
 GO:0006397; P:mRNA processing; TAS:MGI. 

Interpro

 IPR004087; KH_dom.
 IPR004088; KH_dom_type_1. 

Pfam

 PF00013; KH_1 

SMART

 SM00322; KH 

PROSITE

 PS50084; KH_TYPE_1 

PRINTS