CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042421
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 BTB/POZ domain-containing protein KCTD3 
Protein Synonyms/Alias
  
Gene Name
 KCTD3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
58VHRSPVTKIMLSEKHubiquitination[1, 2, 3, 4]
135DQQVFIQKVVPITNKubiquitination[1]
142KVVPITNKLFVRLSSubiquitination[1, 4]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 168 AA 
Protein Sequence
XALSVYLTPK TSVSGNWIEI AYGTSSGAVR VIVQHPETVG SGPQLFQTFT VHRSPVTKIM 60
LSEKHLVSVC ADNNHVRTWT VTRFRGMIST QPGSTPLASF KILSLEETES HGSYSSGNDI 120
GPFGERDDQQ VFIQKVVPIT NKLFVRLSST GKSLCGVSLV SRSSQEPT 168 
Gene Ontology
  
Interpro
 IPR001680; WD40_repeat. 
Pfam
  
SMART
 SM00320; WD40 
PROSITE
  
PRINTS