CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010148
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Replicative DNA helicase 
Protein Synonyms/Alias
  
Gene Name
 dnaB 
Gene Synonyms/Alias
 MPN_232; MP599 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
11NKLEQTFKFANDKNIacetylation[1]
16TFKFANDKNIERAERacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 
Functional Description
 Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity (By similarity). 
Sequence Annotation
 DOMAIN 191 469 SF4 helicase.
 NP_BIND 222 229 ATP (Potential).  
Keyword
 ATP-binding; Complete proteome; DNA replication; DNA-binding; Helicase; Hydrolase; Nucleotide-binding; Primosome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 473 AA 
Protein Sequence
MVSNKLEQTF KFANDKNIER AERVLMQALV QDAVGVDLIL TKLEPKDFFG FPFNFIFQTA 60
QENYSEGNKL FGSALLEAVK FKLDTDSKTQ REIEGLFEDV LLKGLPFLER DIKVFVDVVK 120
KASIFRQLKQ FAKKVEKEEF KVKDDRFEGY LQAIQNDFTK IIHSAFVSIP GLSYDEIVRE 180
EEELIPKVYR GELTVKGLKS GFYPLDQLTS GWKEGELIVV AARPGRGKTA LLINFLQGAV 240
NDSEKFDKNK DVLLFFSLEM RNREIYQRHL MLESQVNYTL TSRQRLANVY DDLIKASEVL 300
RDLPIKIFDY STITLDEIRA QITEVSKTNN VKLVVIDYLQ LVNAFKNSYN ISRQQEVTMI 360
SKSLKSFAKE FNVPIIAAAQ LSRRIEERKD SRPILSDLRE SGSIEQDADM VLFIHRVKDE 420
DSENQEAIGH NNIFQVELIL EKNRSGPTGK VQFDFQSDVS TFRVREYNPD GYS 473 
Gene Ontology
 GO:1990077; C:primosome complex; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003678; F:DNA helicase activity; IEA:InterPro.
 GO:0032508; P:DNA duplex unwinding; IEA:GOC.
 GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-KW. 
Interpro
 IPR007694; DNA_helicase_DnaB-like_C.
 IPR027417; P-loop_NTPase. 
Pfam
 PF03796; DnaB_C 
SMART
  
PROSITE
 PS51199; SF4_HELICASE 
PRINTS