UniProt Accession

 C9JXM5_HUMAN; C9JXM5 

Genbank Protein ID

 AC092927; AC106708; CH471052 

Genbank Nucleotide ID

 EAW78727.1 

Protein Name

 TCDD-inducible poly [ADP-ribose] polymerase 

Protein Synonyms/Alias

 TCDD-inducible poly(ADP-ribose) polymerase, isoform CRA_c 

Gene Name

 TIPARP 

Gene Synonyms/Alias

 hCG_27716 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
259	IYGRDCLKHHTVLPY	ubiquitination	[1]
277	IKRTTTQKWQSVFND	ubiquitination	[2]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 506 AA 

Protein Sequence

Gene Ontology

 GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0008209; P:androgen metabolic process; IEA:Compara.
 GO:0008210; P:estrogen metabolic process; IEA:Compara.
 GO:0060325; P:face morphogenesis; IEA:Compara.
 GO:0008585; P:female gonad development; IEA:Compara.
 GO:0030097; P:hemopoiesis; IEA:Compara.
 GO:0001822; P:kidney development; IEA:Compara.
 GO:0044236; P:multicellular organismal metabolic process; IEA:Compara.
 GO:0006807; P:nitrogen compound metabolic process; IEA:Compara.
 GO:0060021; P:palate development; IEA:Compara.
 GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Compara.
 GO:0009791; P:post-embryonic development; IEA:Compara.
 GO:0006471; P:protein ADP-ribosylation; IEA:Compara.
 GO:0048705; P:skeletal system morphogenesis; IEA:Compara.
 GO:0048745; P:smooth muscle tissue development; IEA:Compara.
 GO:0001570; P:vasculogenesis; IEA:Compara. 

Interpro

 IPR012317; Poly(ADP-ribose)pol_cat_dom.
 IPR004170; WWE-dom.
 IPR000571; Znf_CCCH. 

Pfam

  

SMART

  

PROSITE

 PS51059; PARP_CATALYTIC
 PS50918; WWE
 PS50103; ZF_C3H1 

PRINTS