CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035037
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein LOC100363253 
Protein Synonyms/Alias
  
Gene Name
 Nt5c2 
Gene Synonyms/Alias
 LOC100363253 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
14NRSLAMEKIKCFGFDacetylation[1]
109TREQYPNKFIQRDDTacetylation[1]
180AVDWVHYKGSLKEKTacetylation[1]
193KTVENLEKYVVKDGKacetylation[1]
200KYVVKDGKLPLLLSRacetylation[1]
223LATNSDYKYTDKIMTacetylation[1]
313DLLGAKGKDILYIGDacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 ACT_SITE 21 21 Nucleophile (By similarity).
 ACT_SITE 23 23 Proton donor (By similarity).
 METAL 21 21 Magnesium (By similarity).
 METAL 23 23 Magnesium; via carbonyl oxygen (By
 METAL 320 320 Magnesium (By similarity).  
Keyword
 Complete proteome; Magnesium; Metal-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 529 AA 
Protein Sequence
FYRVFVNRSL AMEKIKCFGF DMDYTLAVYK SPEYESLGFE LTVERLVSIG YPQELLNFAY 60
DSTFPTRGLV FDTLYGNLLK VDAYGNLLVC AHGFNFIRGP ETREQYPNKF IQRDDTERFY 120
ILNTLFNLPE TYLLACLVDF FTNCPRYTSC DTGFKDGDLF MSYRSMFQDV RDAVDWVHYK 180
GSLKEKTVEN LEKYVVKDGK LPLLLSRMKE VGKVFLATNS DYKYTDKIMT YLFDFPHGPK 240
PGSSHRPWQS YFDLILVDAR KPLFFGEGTV LRQVDTKTGK LKIGTYTGPL QHGIVYSGGS 300
SDTICDLLGA KGKDILYIGD HIFGDILKSK KRQGWRTFLV IPELAQELHV WTDKSSLFEE 360
LQSLDIFLAE LYKHLDSSSN ERPDISSIQR RIKKVTHDMD MCYGMMGSLF RSGSRQTLFA 420
SQVMRYADLY AASFINLLYY PFSYLFRAAH VLMPHESTVE HTHVDINEME SPLATRNRTS 480
VDFKDTDYKR HQLTRSISEI KPPNLFPLAP QEITHCHDED DDEEEEEEE 529 
Gene Ontology
 GO:0008253; F:5'-nucleotidase activity; IDA:RGD.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0046085; P:adenosine metabolic process; IDA:RGD.
 GO:0046040; P:IMP metabolic process; IDA:RGD. 
Interpro
 IPR023214; HAD-like_dom.
 IPR008380; HAD-SF_hydro_IG_5-nucl.
 IPR016695; Pur_nucleotidase. 
Pfam
 PF05761; 5_nucleotid 
SMART
  
PROSITE
  
PRINTS