CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009485
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein BTG1 
Protein Synonyms/Alias
 B-cell translocation gene 1 protein 
Gene Name
 BTG1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
75RCIRINHKMDPLIGQubiquitination[1]
162LGRTSPSKNYNMMTVubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
 Anti-proliferative protein. 
Sequence Annotation
  
Keyword
 Chromosomal rearrangement; Complete proteome; Polymorphism; Proto-oncogene; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 171 AA 
Protein Sequence
MHPFYTRAAT MIGEIAAAVS FISKFLRTKG LTSERQLQTF SQSLQELLAE HYKHHWFPEK 60
PCKGSGYRCI RINHKMDPLI GQAAQRIGLS SQELFRLLPS ELTLWVDPYE VSYRIGEDGS 120
ICVLYEASPA GGSTQNSTNV QMVDSRISCK EELLLGRTSP SKNYNMMTVS G 171 
Gene Ontology
 GO:0005737; C:cytoplasm; IMP:UniProtKB.
 GO:0005634; C:nucleus; IDA:UniProtKB.
 GO:0019900; F:kinase binding; NAS:UniProtKB.
 GO:0003712; F:transcription cofactor activity; NAS:UniProtKB.
 GO:0016477; P:cell migration; NAS:UniProtKB.
 GO:0030308; P:negative regulation of cell growth; NAS:UniProtKB.
 GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
 GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
 GO:0045603; P:positive regulation of endothelial cell differentiation; IMP:UniProtKB.
 GO:0045663; P:positive regulation of myoblast differentiation; NAS:UniProtKB.
 GO:0006479; P:protein methylation; IEA:Compara.
 GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.
 GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.
 GO:0006979; P:response to oxidative stress; IEA:Compara.
 GO:0043434; P:response to peptide hormone stimulus; IEA:Compara.
 GO:0007283; P:spermatogenesis; IEA:Compara. 
Interpro
 IPR002087; Anti_prolifrtn. 
Pfam
 PF07742; BTG 
SMART
 SM00099; btg1 
PROSITE
 PS00960; BTG_1
 PS01203; BTG_2 
PRINTS
 PR00310; ANTIPRLFBTG1.