| Tag | Content |
|---|
| CPLM ID | CPLM-016122 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein zer-1 homolog |
Protein Synonyms/Alias | Zyg-11 homolog B-like protein |
Gene Name | Zer1 |
Gene Synonyms/Alias | Zyg; Zyg11bl |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 31 | TLGYLLDKETLRLHP | ubiquitination | [1] | | 102 | QDLEAIRKQDLVELY | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZER1-CUL2-Elongin BC (By similarity). |
Sequence Annotation | REPEAT 226 245 LRR 1.
REPEAT 246 281 LRR 2.
REPEAT 291 315 LRR 3.
REPEAT 440 480 ARM 1.
REPEAT 524 569 ARM 2.
REPEAT 571 613 ARM 3.
REPEAT 615 656 ARM 4.
REPEAT 727 769 ARM 5. |
Keyword | Alternative splicing; Complete proteome; Direct protein sequencing; Leucine-rich repeat; Reference proteome; Repeat; Ubl conjugation pathway. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 779 AA |
Protein Sequence | MASDTPESLM ALCTDFCLRN LDGTLGYLLD KETLRLHPDI FLPSEICDQL VNEYVELVSA 60
ACTFEPHETF FSLFSDPRST RLTRIHLRED LVQDQDLEAI RKQDLVELYL TNCEKLSAKS 120
LQTLRSFRHS LVSLSLSGCA NIFYEEDNPG GCEDECLVNP TCQVLVKDFT FEGFSRLRFL 180
NLGRMIDGIP VESLLRPLNS LAALDLSGIQ TSDATFLTQW KDSLMSLVLY NMDLSDDHIR 240
VIVQLHKLRS KILTCGPHLI SSHLDISRDR LSSYYKFKLT RKVLSLLVQK LGNLMSLDIS 300
GHMILENCSI SKTDEEAGQT STEPSKSSIM PFRALKRPLQ FLGLFETSLC RLTHIPAYKV 360
SGDKNEEQVL NAIEAYTEHR PEITSRAINL LFDIARIERC NQLLRALKLV ITALKCHKYD 420
KNIQVTGSAA LFYLTNSEYR SEQSVKLRRQ VIQVVLNGME SYQEVTVQRN CCLTLCNFSI 480
PEELEFQYRR VNELLLGILS PTRQDESIQR IAVHLCNALV CQVDNDHKEA VGKMGFVVTM 540
LKLIQKKLLD KTCDQVMEFS WSALWNITDE TPDNCEMFLN FNGMKLFLDC LKEFPEKQEL 600
HRNMLGLLGN VAEVKELRPQ LMTSQFISVF SNLLESKADG IEVSYNACGV LSHIMFDGPE 660
AWGVCEPQRA EVEDRMWAAI QSWDINSRRN INYRSFEPIL RLLPQGISPV SQHWATWALY 720
NLVSVYPDKY CPLLIKEGGM PLLRDLIKMA TARQETKEMA RKVIEHCSNF REENMDTSR 779 |
Gene Ontology | GO:0031462; C:Cul2-RING ubiquitin ligase complex; ISS:UniProtKB. GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. GO:0051438; P:regulation of ubiquitin-protein ligase activity; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |