CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034679
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Pkn3 
Protein Synonyms/Alias
  
Gene Name
 Pkn3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
198QASEEILKVEQKYNKacetylation[1]
202EILKVEQKYNKLRQPacetylation[1]
213LRQPFFQKRSELIAKacetylation[1]
262VTEFEDIKSGYRIDFacetylation[1]
280ENPYFENKVLSKEFHacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 958 AA 
Protein Sequence
MAPKRQSAIL PQPETQTRCC PEAGGQVGLS RPAEGSTFLV LRSDSGFRAS VHFSLSSVDR 60
EVCVSYAQLR VVVWCFPRGL LGSVCFLHSS CEVHNPISGM PRGSSVEQAL GSMLAVVTST 120
NPWIRRCMCW RSLCLGAVRF LSGVFSESVQ KSCTAVYDDQ SSRMGWKKKE QQEAIEHIDE 180
VQNEIDRLNE QASEEILKVE QKYNKLRQPF FQKRSELIAK IPNFWVTTFV NHPQVSALLG 240
EEDEEALHYL TRVEVTEFED IKSGYRIDFY FDENPYFENK VLSKEFHLNE SGDPSSKETG 300
ARHRQGRERK LLAAAQQMLK DSQLKVALLR MKISGLEASG SPEPGPDLLA EELQHRLRIE 360
AAVAAGAKNV VKLLGGQRIQ DRKALAEAQA QLQESSQKLD LLRLALELLL ERLPPTHSLR 420
SRVTRELRMA MLGNPQPLGT LVKPIALTGE VLAVLKVDNR VVGQTGWGLV AEKSWDQAFS 480
ISLDRVTFCE PVIERRPRLQ RQRRVFSKRR GQDFLRASQM NLSMTAWGRL VMSLLPPCSS 540
PSTVSPPKGC PSAAACETSS SASPSMVMRL PAPCDWAQTF PSYSNFRPVK TLPGEDMKPP 600
PKPPRLYLQE PAPGTPCTKR PHMDPRTGVA PPLAALSTRN PPQLQDFRCL AVLGRGHFGK 660
VLLVQYKGTG KYYAIKALKK QEVLGRDEID SLYCEKRILE TVGRTGHPFL LSLLACIQTS 720
SHACFVTEFL PGGDLMMQIH EDVFPEPQAC FYLACVVLGL QFLHEKRIIY RDLKLDNLLL 780
DAQGFLKIAD FGLCKEGIGF GDRTSTFCGT PEFLAPEVLT QEAYTRAVDW WGLGVLLYEM 840
LVGDTEDEVF ECIVNADVPC PHFLSAQGLE LIQKLLQKSP EKRLGAGERD AEEIKVQPFF 900
RPPFVPTLCG PADLRYFEGE FTSLPPTLTP PVPRRSLSAR QQAAFRDFDF VSKRFLES 958 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
 GO:0006334; P:nucleosome assembly; IEA:InterPro.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR000961; AGC-kinase_C.
 IPR011072; HR1_rho-bd.
 IPR011009; Kinase-like_dom.
 IPR002164; NAP_family.
 IPR017892; Pkinase_C.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS. 
Pfam
 PF02185; HR1
 PF00956; NAP
 PF00069; Pkinase
 PF00433; Pkinase_C 
SMART
 SM00742; Hr1
 SM00133; S_TK_X
 SM00220; S_TKc 
PROSITE
 PS51285; AGC_KINASE_CTER
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 
PRINTS