CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025959
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 NFX1-type zinc finger-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 ZNFX1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
293DIEEETEKNLEKVQTubiquitination[1, 2]
308IIEHLQEKRREGTLRubiquitination[2]
435YKVQFDTKPLKFVRWubiquitination[2]
544VECNSHVKEPRYLLMubiquitination[2, 3, 4]
593DPGQWPSKEALKLDDubiquitination[1]
690RSNSEILKQFTLRELubiquitination[2]
734QELHEGAKTLECTMRubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 934 AA 
Protein Sequence
MEERRPHLDA RPRNSHTNHR GPVDGELPPR ARNQANNPPA NALRGGASHP GRHPRANNHP 60
AAYWQREERF RAMGRNPHQG RRNQEGHASD EARDQRHDQE NDTRWRNGNQ DCRNRRPPWS 120
NDNFQQWRTP HQKPTEQPQQ AKKLGYKFLE SLLQKDPSEV VITLATSLGL KELLSHSSMK 180
SNFLELICQV LRKACSSKMD RQSVLHVLGI LKNSKFLKVC LPAYVVGMIT EPIPDIRNQY 240
PEHISNIISL LQDLVSVFPA SSVQETSMLV SLLPTSLNAL RASGVDIEEE TEKNLEKVQT 300
IIEHLQEKRR EGTLRVDTYT LVQPEAEDHV ESYRTMPIYP TYNEVHLDER PFLRPNIISG 360
KYDSTAIYLD THFRLLREDF VRPLREGILE LLQSFEDQGL RKRKFDDIRI YFDTRIITPM 420
CSSSGIVYKV QFDTKPLKFV RWQNSKRLLY GSLVCMSKDN FETFLFATVS NREQEDLCRG 480
IVQLCFNEQS QQLLAEVQPS DSFLMVETTA YFEAYRHVLE GLQEVQEEDV PFQRNIVECN 540
SHVKEPRYLL MGGRYDFTPL IENPSATGEF LRNVEGLRHP RINVLDPGQW PSKEALKLDD 600
SQMEALQFAL TRELAIIQGP PGTGKTYVGL KIVQALLTNE SVWQISLQKF PILVVCYTNH 660
ALDQFLEGIY NCQKTSIVRV GGRSNSEILK QFTLRELRNK REFRRNLPMH LRRAYMSIMT 720
QMKESEQELH EGAKTLECTM RGVLREQYLQ KYISPQHWES LMNGPVQDSE WICFQHWKHS 780
MMLEWLGLGV GSFTQSVSPA GPENTAQAEG DEEEEGEEES SLIEIAEEAD LIQADRVIEE 840
EEVVRPQRRK KEESGADQEL AKMLLAMRLD HCGTGTAAGQ EQATGEWQTQ RNQKKKMKKR 900
VKDELRKLNT MTAAEANEIE DVWQLDLSSR WQLY 934 
Gene Ontology
  
Interpro
 IPR027417; P-loop_NTPase. 
Pfam
  
SMART
  
PROSITE
  
PRINTS