CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007464
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Centrin-1 
Protein Synonyms/Alias
 Caltractin 
Gene Name
 Cetn1 
Gene Synonyms/Alias
 Calt 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
120FDDDETGKISFKNLKubiquitination[1]
124ETGKISFKNLKRVANubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Plays a fundamental role in microtubule-organizing center structure and function. 
Sequence Annotation
 DOMAIN 28 63 EF-hand 1.
 DOMAIN 64 99 EF-hand 2.
 DOMAIN 101 136 EF-hand 3.
 DOMAIN 137 172 EF-hand 4.  
Keyword
 Calcium; Cell cycle; Cell division; Complete proteome; Cytoplasm; Cytoskeleton; Metal-binding; Mitosis; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 172 AA 
Protein Sequence
MASTFRKSNV ASTSYKRKVG PKPELTEDQK QEVREAFDLF DSDGSGTIDV KELKVAMRAL 60
GFEPRKEEMK KMISEVDKEA TGKISFNDFL AVMTQKMAEK DTKEEILKAF RLFDDDETGK 120
ISFKNLKRVA NELGESLTDE ELQEMIDEAD RDGDGEVNEE EFLKIMKKTN LY 172 
Gene Ontology
 GO:0005813; C:centrosome; IDA:MGI.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0032391; C:photoreceptor connecting cilium; IDA:MGI.
 GO:0000922; C:spindle pole; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0031683; F:G-protein beta/gamma-subunit complex binding; IDA:MGI.
 GO:0032795; F:heterotrimeric G-protein binding; IDA:MGI.
 GO:0008017; F:microtubule binding; IDA:MGI.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0034605; P:cellular response to heat; IDA:MGI.
 GO:0007067; P:mitosis; IEA:UniProtKB-KW. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR000629; RNA-helicase_DEAD-box_CS. 
Pfam
 PF13499; EF_hand_5 
SMART
 SM00054; EFh 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 
PRINTS