CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-007464
UniProt Accession
CETN1_MOUSE
;
P41209
;
Q3V119
;
Q9D9G9
;
Q9DAL6
Genbank Protein ID
D16301
;
AF080591
;
AK005736
;
AK005743
;
AK005837
;
AK006940
;
AK015808
;
AK076986
;
AK132753
;
BC048488
;
BC061155
Genbank Nucleotide ID
BAA03806.1
;
AAD46390.1
;
BAB24213.1
;
BAB24217.1
;
BAB24266.1
;
BAB24798.1
;
BAB29985.1
;
BAC36550.1
;
BAE21334.1
;
AAH48488.1
;
AAH61155.1
Protein Name
Centrin-1
Protein Synonyms/Alias
Caltractin
Gene Name
Cetn1
Gene Synonyms/Alias
Calt
Created Date
July 27, 2013
Organism
Mus musculus (Mouse)
NCBI Taxa ID
10090
Lysine Modification
Position
Peptide
Type
References
120
FDDDETG
K
ISFKNLK
ubiquitination
[1]
124
ETGKISF
K
NLKRVAN
ubiquitination
[1]
Reference
[1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [
PMID: 22790023
]
Functional Description
Plays a fundamental role in microtubule-organizing center structure and function.
Sequence Annotation
DOMAIN 28 63 EF-hand 1.
DOMAIN 64 99 EF-hand 2.
DOMAIN 101 136 EF-hand 3.
DOMAIN 137 172 EF-hand 4.
Keyword
Calcium; Cell cycle; Cell division; Complete proteome; Cytoplasm; Cytoskeleton; Metal-binding; Mitosis; Reference proteome; Repeat.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
172 AA
Protein Sequence
MASTFRKSNV ASTSYKRKVG PKPELTEDQK QEVREAFDLF DSDGSGTIDV KELKVAMRAL 60
GFEPRKEEMK KMISEVDKEA TGKISFNDFL AVMTQKMAEK DTKEEILKAF RLFDDDETGK 120
ISFKNLKRVA NELGESLTDE ELQEMIDEAD RDGDGEVNEE EFLKIMKKTN LY 172
Gene Ontology
GO:0005813
; C:centrosome; IDA:MGI.
GO:0005737
; C:cytoplasm; IEA:UniProtKB-KW.
GO:0032391
; C:photoreceptor connecting cilium; IDA:MGI.
GO:0000922
; C:spindle pole; IEA:Compara.
GO:0005524
; F:ATP binding; IEA:InterPro.
GO:0008026
; F:ATP-dependent helicase activity; IEA:InterPro.
GO:0005509
; F:calcium ion binding; IEA:InterPro.
GO:0031683
; F:G-protein beta/gamma-subunit complex binding; IDA:MGI.
GO:0032795
; F:heterotrimeric G-protein binding; IDA:MGI.
GO:0008017
; F:microtubule binding; IDA:MGI.
GO:0003676
; F:nucleic acid binding; IEA:InterPro.
GO:0051301
; P:cell division; IEA:UniProtKB-KW.
GO:0034605
; P:cellular response to heat; IDA:MGI.
GO:0007067
; P:mitosis; IEA:UniProtKB-KW.
Interpro
IPR011992
; EF-hand-like_dom.
IPR018247
; EF_Hand_1_Ca_BS.
IPR002048
; EF_hand_dom.
IPR000629
; RNA-helicase_DEAD-box_CS.
Pfam
PF13499
; EF_hand_5
SMART
SM00054
; EFh
PROSITE
PS00018
; EF_HAND_1
PS50222
; EF_HAND_2
PRINTS