CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013086
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Disco-interacting protein 2 homolog B 
Protein Synonyms/Alias
 DIP2 homolog B 
Gene Name
 Dip2b 
Gene Synonyms/Alias
 Kiaa1463 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
47GYEKKRSKLLSPYSPubiquitination[1]
65ETDSIGQKERNQTPAubiquitination[1]
273VNSRVSTKIQQLLNTubiquitination[1]
478NGEIVQFKGWPRLKWubiquitination[1]
964VGNLVAGKRIAQAAGubiquitination[1]
1298SLQQSFSKLFKDIGLubiquitination[1]
1365LLLSESGKILPGVKVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 MOD_RES 50 50 Phosphoserine (By similarity).
 MOD_RES 53 53 Phosphoserine (By similarity).
 MOD_RES 70 70 Phosphothreonine (By similarity).
 MOD_RES 99 99 Phosphoserine.
 MOD_RES 139 139 Phosphothreonine (By similarity).
 MOD_RES 145 145 Phosphoserine (By similarity).
 MOD_RES 147 147 Phosphoserine (By similarity).
 MOD_RES 152 152 Phosphoserine.
 MOD_RES 202 202 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1574 AA 
Protein Sequence
MAERGLEPSP AAVAALPPEV RAQLAELELE LSEGDITQKG YEKKRSKLLS PYSPQTQETD 60
SIGQKERNQT PAPTAAQTSA PSKYHRSRSG GARDERYRSD IHTEAVQAAL AKHKEQKMAL 120
PMPTKRRSTF VQSPADACTP PDTSSASEDE GSLRRQAALS AALQQSLQNA ESWINRSIQG 180
SSTSSSASST LSHGEVKGTS GSLADVFANT RIENVSAPPD VTATTSSSSS SLRPANIDLP 240
PSGIVKGMHK GSNRSSLMDT ADGVPVNSRV STKIQQLLNT LKRPKRPPLK EFFVDDSEEI 300
VEGIPQPDPN QPKPEGRQMT PVKGEPLGVI CNWPPALESA LQRWGSTQAK CPCLTGLDVT 360
GKPVYTLTYG KLWSRSLKLA YTLLNKLGTK NEPVLKPGDR VALVYPNNDP VMFMVAFYGC 420
LLAEVIPVPI EVPLTRKDAG GQQIGFLLGS CGIALALTSE ICLKGLPKTQ NGEIVQFKGW 480
PRLKWVVTDS KYLSKPPKDW QPHISPAGTE PAYIEYKTSK EGSVMGVTVS RLAMLSQCQA 540
LSQACNYSEG ETVVNVLDFK KDAGLWHGMF ANVMNKMHTI SVPYSVMKTC PLSWVQRVHA 600
HKAKVALVKC RDLHWAMMAH RDQRDVSLSS LRMLIVTDGA NPWSVSSCDA FLSLFQSHGL 660
KPEAICPCAT SAEAMTVAIR RPGVPGAPLP GRAILSMNGL SYGVIRVNTE DKNSALTVQD 720
VGHVMPGGMM CIVKPDGLPQ LCRTDEIGEI CVSSRTGGMM YFGLAGVTKN TFEVIPVTSS 780
GSPVGDVPFI RSGLLGFVGP GSLVFVVGKM DGLLMVSGRR HNADDIVATG LAVESIKTVY 840
RGRIAVFSVS VFYDERIVVV AEQRPDASEE DSFQWMSRVL QAIDSIHQVG VYCLALVPAN 900
TLPKTPLGGI HISQTKQLFL EGSLHPCNIL MCPHTCVTNL PKPRQKQPGV GPASVMVGNL 960
VAGKRIAQAA GRDLGQIEEN DLVRKHQFLA EILQWRAQAT PDHVLFMLLN AKGTTVCTAS 1020
CLQLHKRAER IASVLGDKGH LNAGDNVVLL YPPGIELIAA FYGCLYAGCI PVTVRPPHAQ 1080
NLTATLPTVR MVVDVSKAAC VLTTQTLMRL LKSREAAAAV DVKTWPAIID TDDLPRKRLP 1140
QLYKPPTPEM LAYLDFSVST TGMLTGVKMS HSAVNALCRA IKLQCELYSS RQIAICLDPY 1200
CGLGFALWCL CSVYSGHQSV LIPPMELENN LFLWLATVNQ YKIRDTFCSY SVMELCTKGL 1260
GNQVEVLKTR GINLSCIRTC VVVAEERPRV SLQQSFSKLF KDIGLSPRAV STTFGSRVNV 1320
AICLQGTSGP DPTTVYVDLK SLRHDRVRLV ERGAPQSLLL SESGKILPGV KVVIVNPETK 1380
GPVGDSHLGE IWVNSPHTAS GYYTIYDSET LQADHFNTRL SFGDAAQTLW ARTGYLGFVR 1440
RTELTAATGE RHDALYVVGA LDETLELRGL RYHPIDIETS VSRVHRSIAE CAVFTWTNLL 1500
VVVVELCGSE QEALDLVPLV TNVVLEEHYL IVGVVVVVDP GVVPINSRGE KQRMHLRDSF 1560
LADQLDPIYV AYNM 1574 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0003824; F:catalytic activity; IEA:InterPro. 
Interpro
 IPR000873; AMP-dep_Synth/Lig.
 IPR010506; DMAP1-bd. 
Pfam
 PF00501; AMP-binding
 PF06464; DMAP_binding 
SMART
  
PROSITE
  
PRINTS