| Tag | Content |
|---|
| CPLM ID | CPLM-016244 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 410 |
Protein Synonyms/Alias | Another partner for ARF 1; Zinc finger protein APA-1 |
Gene Name | ZNF410 |
Gene Synonyms/Alias | APA1 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 254 | FVWPAHFKYHLKTHR | ubiquitination | [1] | | 275 | CPAEGCGKSFYVLQR | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Transcription factor that activates transcription of matrix-remodeling genes such as MMP1 during fibroblast senescence. |
Sequence Annotation | ZN_FING 219 243 C2H2-type 1.
ZN_FING 249 273 C2H2-type 2.
ZN_FING 279 303 C2H2-type 3.
ZN_FING 309 333 C2H2-type 4.
ZN_FING 339 362 C2H2-type 5. |
Keyword | Activator; Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Ubl conjugation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 478 AA |
Protein Sequence | MLSDELESKP ELLVQFVQNT SIPLGQGLVE SEAKDITCLS LLPVTEASEC SRLMLPEPVP 60
WREEDGKSGC SDLNDTTNHS NSSKEVPSSA VLRSLRVNVG PDGEETRAQT VQKSPEFLST 120
SESSSLLQDL QPSDSTSFIL LNLTRAGLGS SAEHLVFVQD EAEDSGNDFL SSESTDSSIP 180
WFLRVQELAH DSLIAATRAQ LAKNAKTSSN GENVHLGSGD GQSKDSGPLP QVEKKLKCTV 240
EGCDRTFVWP AHFKYHLKTH RNDRSFICPA EGCGKSFYVL QRLKVHMRTH NGEKPFMCHE 300
SGCGKQFTTA GNLKNHRRIH TGEKPFLCEA QGCGRSFAEY SSLRKHLVVH SGEKPHQCQV 360
CGKTFSQSGS RNVHMRKHHL QLGAAGSQEQ EQTAEPLMGS SLLEEASVPS KNLVSMNSQP 420
SLGGESLNLP NTNSILGVDD EVLAEGSPRS LSSVPDVTHH LVTMQSGRQS YEVSVLTAVN 480
PQESLAPLPR LECSGAFSAH CNLCLPGSSD SPASAS 516 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |