UniProt Accession

 TPC2L_HUMAN; Q9UL33; B2R4M9; Q6ZTA7; Q9NZZ4 

Genbank Protein ID

 AF089106; AF161524; AK126779; AK311885; AC092384; BC011369; BC018024; BC105809 

Genbank Nucleotide ID

 AAF00568.1; AAF29139.1; BAC86686.1; BAG34826.1; AAH11369.1; AAH18024.1; AAI05810.1 

Protein Name

 Trafficking protein particle complex subunit 2-like protein 

Protein Synonyms/Alias

  

Gene Name

 TRAPPC2L 

Gene Synonyms/Alias

 HSPC126 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
48	EKISAMGKALVDQRE	ubiquitination	[1, 2, 3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

 May play a role in vesicular transport from endoplasmic reticulum to Golgi. 

Sequence Annotation

  

Keyword

 Alternative splicing; Complete proteome; Cytoplasm; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 140 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:InterPro. 

Interpro

 IPR011012; Longin-like_dom.
 IPR006722; Sedlin. 

Pfam

 PF04628; Sedlin_N 

SMART

  

PROSITE

  

PRINTS