CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043667
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Kinetochore-associated protein NSL1 homolog 
Protein Synonyms/Alias
  
Gene Name
 NSL1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
59LCGRFVQKLGDALPEubiquitination[1, 2]
125IIVDIATKRKQYPRKubiquitination[1, 3, 4]
132KRKQYPRKILECVIKubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 240 AA 
Protein Sequence
MAGSPELVVL DPPWDKELAA GTESQALVSA TPREDFRVRC TSKRAVTEML QLCGRFVQKL 60
GDALPEEIRE PALRDAQWTF ESAVQENISI NGQAWQEASD NCFMDSDIKV LEDQFDEIIV 120
DIATKRKQYP RKILECVIKT IKAKQEILSL PALIEQGEGF SQVLRMQPVI HLQRIHQEVF 180
SSCHRKPDAK PENFITQIET TPTETASRKT SDMVLKRKQT KDCPQRKWYP LRPKKINLDT 240 
Gene Ontology
  
Interpro
 IPR013950; Kinetochore_Mis14. 
Pfam
 PF08641; Mis14 
SMART
  
PROSITE
  
PRINTS