UniProt Accession

 TB182_HUMAN; Q9C0C2; A7E2F8; Q6PJ35; Q6ZV74 

Genbank Protein ID

 AF441771; AB051528; AK124903; AP000781; CH471076; BC023622; BC150333; AK074113 

Genbank Nucleotide ID

 AAM15531.1; BAB21832.2; BAC85989.1; EAW73731.1; AAH23622.1; AAI50334.1; BAB84939.1 

Protein Name

 182 kDa tankyrase-1-binding protein 

Protein Synonyms/Alias

  

Gene Name

 TNKS1BP1 

Gene Synonyms/Alias

 KIAA1741; TAB182 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
1644	SLGTKGLKVNLFPGL	ubiquitination	[1]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

 REGION 210 1572 Acidic.
 REGION 1450 1542 Tankyrase-binding.
 MOTIF 1629 1635 Nuclear localization signal (Potential).
 MOTIF 1723 1729 Nuclear localization signal (Potential).
 MOD_RES 178 178 Phosphoserine.
 MOD_RES 221 221 Phosphoserine.
 MOD_RES 239 239 Phosphothreonine.
 MOD_RES 429 429 Phosphoserine.
 MOD_RES 435 435 Phosphoserine.
 MOD_RES 437 437 Phosphoserine.
 MOD_RES 494 494 Phosphoserine.
 MOD_RES 498 498 Phosphoserine.
 MOD_RES 601 601 Phosphoserine.
 MOD_RES 672 672 Phosphoserine.
 MOD_RES 691 691 Phosphoserine.
 MOD_RES 695 695 Phosphoserine.
 MOD_RES 712 712 Phosphoserine.
 MOD_RES 744 744 Phosphoserine.
 MOD_RES 762 762 Phosphoserine.
 MOD_RES 833 833 Phosphothreonine.
 MOD_RES 836 836 Phosphoserine.
 MOD_RES 851 851 Phosphoserine.
 MOD_RES 872 872 Phosphoserine.
 MOD_RES 877 877 Phosphoserine.
 MOD_RES 882 882 Phosphoserine.
 MOD_RES 893 893 Phosphoserine.
 MOD_RES 899 899 Phosphoserine.
 MOD_RES 920 920 Phosphoserine.
 MOD_RES 936 936 Phosphoserine.
 MOD_RES 979 979 Phosphothreonine.
 MOD_RES 983 983 Phosphoserine.
 MOD_RES 987 987 Phosphoserine.
 MOD_RES 1008 1008 Phosphoserine.
 MOD_RES 1024 1024 Phosphoserine.
 MOD_RES 1029 1029 Phosphoserine.
 MOD_RES 1054 1054 Phosphoserine.
 MOD_RES 1103 1103 Phosphoserine.
 MOD_RES 1133 1133 Phosphoserine.
 MOD_RES 1138 1138 Phosphoserine.
 MOD_RES 1178 1178 Phosphoserine.
 MOD_RES 1248 1248 Phosphoserine.
 MOD_RES 1253 1253 Phosphoserine.
 MOD_RES 1282 1282 Phosphothreonine.
 MOD_RES 1297 1297 Phosphoserine.
 MOD_RES 1328 1328 Phosphoserine.
 MOD_RES 1331 1331 Phosphoserine.
 MOD_RES 1383 1383 Phosphoserine.
 MOD_RES 1385 1385 Phosphoserine.
 MOD_RES 1439 1439 Phosphoserine.
 MOD_RES 1452 1452 Phosphoserine (By similarity).
 MOD_RES 1533 1533 Phosphoserine.
 MOD_RES 1545 1545 Phosphoserine.
 MOD_RES 1558 1558 Phosphoserine.
 MOD_RES 1563 1563 Phosphothreonine.
 MOD_RES 1620 1620 Phosphoserine.
 MOD_RES 1621 1621 Phosphoserine.
 MOD_RES 1631 1631 Phosphoserine.
 MOD_RES 1652 1652 Phosphoserine.
 MOD_RES 1666 1666 Phosphoserine.
 MOD_RES 1715 1715 Phosphoserine.  

Keyword

 ADP-ribosylation; Alternative splicing; Chromosome; Complete proteome; Cytoplasm; Cytoskeleton; Nucleus; Phosphoprotein; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 1729 AA 

Protein Sequence

Gene Ontology

 GO:0030014; C:CCR4-NOT complex; IDA:UniProtKB.
 GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0005724; C:nuclear telomeric heterochromatin; NAS:UniProtKB.
 GO:0030506; F:ankyrin binding; NAS:UniProtKB.
 GO:0019899; F:enzyme binding; NAS:UniProtKB.
 GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
 GO:0007004; P:telomere maintenance via telomerase; NAS:UniProtKB. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS