CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013896
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transmembrane protein 201 
Protein Synonyms/Alias
 Spindle-associated membrane protein 1 
Gene Name
 TMEM201 
Gene Synonyms/Alias
 NET5; SAMP1 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
40YRIARRMKPTHTMVNubiquitination[1]
133HHQTTKIKQLAAFAPubiquitination[1, 2, 3]
192LLLSHQFKRREADQTubiquitination[1, 2, 3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
 Isoform SAMP1 may define a distinct membrane domain in the vicinity of the mitotic spindle. 
Sequence Annotation
 MOD_RES 454 454 Phosphoserine.
 MOD_RES 529 529 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Membrane; Nucleus; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 666 AA 
Protein Sequence
MEGVSALLAR CPTAGLAGGL GVTACAAAGV LLYRIARRMK PTHTMVNCWF CNQDTLVPYG 60
NRNCWDCPHC EQYNGFQENG DYNKPIPAQY LEHLNHVVSS APSLRDPSQP QQWVSSQVLL 120
CKRCNHHQTT KIKQLAAFAP REEGRYDEEV EVYRHHLEQM YKLCRPCQAA VEYYIKHQNR 180
QLRALLLSHQ FKRREADQTH AQNFSSAVKS PVQVILLRAL AFLACAFLLT TALYGASGHF 240
APGTTVPLAL PPGGNGSATP DNGTTPGAEG WRQLLGLLPE HMAEKLCEAW AFGQSHQTGV 300
VALGLLTCLL AMLLAGRIRL RRIDAFCTCL WALLLGLHLA EQHLQAASPS WLDTLKFSTT 360
SLCCLVGFTA AVATRKATGP RRFRPRRFFP GDSAGLFPTS PSLAIPHPSV GGSPASLFIP 420
SPPSFLPLAN QQLFRSPRRT SPSSLPGRLS RALSLGTIPS LTRADSGYLF SGSRPPSQVS 480
RSGEFPVSDY FSLLSGSCPS SPLPSPAPSV AGSVASSSGS LRHRRPLISP ARLNLKGQKL 540
LLFPSPPGEA PTTPSSSDEH SPHNGSLFTM EPPHVPRKPP LQDVKHALDL RSKLERGSAC 600
SNRSIKKEDD SSQSSTCVVD TTTRGCSEEA ATWRGRFGPS LVRGLLAVSL AANALFTSVF 660
LYQSLR 666 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell. 
Interpro
 IPR018617; DUF2349.
 IPR018861; DUF2448. 
Pfam
 PF09779; DUF2349
 PF10476; DUF2448 
SMART
  
PROSITE
  
PRINTS