| Tag | Content |
|---|
| CPLM ID | CPLM-005981 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Dolichyl-phosphate-mannose--protein mannosyltransferase 2 |
Protein Synonyms/Alias | |
Gene Name | PMT2 |
Gene Synonyms/Alias | YAL023C; FUN25 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 11 | SSSTGYSKNNAAHIK | acetylation | [1] | | 18 | KNNAAHIKQENTLRQ | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. Seems to be active on chitinase. |
Sequence Annotation | DOMAIN 339 394 MIR 1.
DOMAIN 407 463 MIR 2.
DOMAIN 471 529 MIR 3.
MOD_RES 32 32 Phosphoserine.
MOD_RES 38 38 Phosphoserine.
MOD_RES 39 39 Phosphoserine.
CARBOHYD 131 131 N-linked (GlcNAc...) (Potential).
CARBOHYD 155 155 N-linked (GlcNAc...) (Potential).
CARBOHYD 403 403 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Endoplasmic reticulum; Glycoprotein; Glycosyltransferase; Membrane; Phosphoprotein; Reference proteome; Repeat; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 759 AA |
Protein Sequence | MSSSSSTGYS KNNAAHIKQE NTLRQRESSS ISVSEELSSA DERDAEDFSK EKPAAQSSLL 60
RLESVVMPVI FTALALFTRM YKIGINNHVV WDEAHFGKFG SYYLRHEFYH DVHPPLGKML 120
VGLSGYLAGY NGSWDFPSGE IYPDYLDYVK MRLFNASFSA LCVPLAYFTA KAIGFSLPTV 180
WLMTVLVLFE NSYSTLGRFI LLDSMLLFFT VASFFSFVMF HNQRSKPFSR KWWKWLLITG 240
ISLGCTISVK MVGLFIITMV GIYTVIDLWT FLADKSMSWK TYINHWLARI FGLIIVPFCI 300
FLLCFKIHFD LLSHSGTGDA NMPSLFQARL VGSDVGQGPR DIALGSSVVS IKNQALGGSL 360
LHSHIQTYPD GSNQQQVTCY GYKDANNEWF FNRERGLPSW SENETDIEYL KPGTSYRLVH 420
KSTGRNLHTH PVAAPVSKTQ WEVSGYGDNV VGDNKDNWVI EIMDQRGDED PEKLHTLTTS 480
FRIKNLEMGC YLAQTGNSLP EWGFRQQEVV CMKNPFKRDK RTWWNIETHE NERLPPRPED 540
FQYPKTNFLK DFIHLNLAMM ATNNALVPDP DKFDYLASSA WQWPTLNVGL RLCGWGDDNP 600
KYFLLGTPAS TWASSVAVLA FMATVVILLI RWQRQYVDLR NPSNWNVFLM GGFYPLLAWG 660
LHYMPFVIMS RVTYVHHYLP ALYFALIILA YCFDAGLQKW SRSKCGRIMR FVLYAGFMAL 720
VIGCFWYFSP ISFGMEGPSS NFRYLNWFST WDIADKQEA 759 |
Gene Ontology | GO:0031502; C:dolichyl-phosphate-mannose-protein mannosyltransferase complex; IPI:SGD. GO:0016021; C:integral to membrane; ISM:SGD. GO:0004169; F:dolichyl-phosphate-mannose-protein mannosyltransferase activity; IDA:SGD. GO:0071712; P:ER-associated misfolded protein catabolic process; IMP:SGD. GO:0032527; P:protein exit from endoplasmic reticulum; IGI:SGD. GO:0035269; P:protein O-linked mannosylation; IMP:SGD. GO:1900101; P:regulation of endoplasmic reticulum unfolded protein response; IGI:SGD. |
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