CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026259
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 FERM domain containing 4A, isoform CRA_b 
Protein Synonyms/Alias
 FERM domain-containing protein 4A 
Gene Name
 FRMD4A 
Gene Synonyms/Alias
 hCG_1811390 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
18RSQRLLLKIPYGSLRubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 450 AA 
Protein Sequence
MVVQAAVAPN RSQRLLLKIP YGSLRRRSVE RMTEGRRCQV HLLDDRKLEL LVQPKLLAKE 60
LLDLVASHFN LKEKEYFGIA FTDETGHLNW LQLDRRVLEH DFPKKSGPVV LYFCVRFYIE 120
SISYLKDNAT IELFFLNAKS CIYKELIDVD SEVVFELASY ILQEAKGDFS SNEVVRSDLK 180
KLPALPTQAL KEHPSLAYCE DRVIEHYKKL NGQTRGQAIV NYMSIVESLP TYGVHYYAVK 240
DKQGIPWWLG LSYKGIFQYD YHDKVKPRKI FQWRQLENLY FREKKFSVEV HDPRRASVTR 300
RTFGHSGIAV HTWYACPALI KSIWAMAISQ HQFYLDRKQS KSKIHAARSL SEIAIDLTET 360
GTLKTSKLAN MGSKGKIISG SSGSLLSSGR QRPAGGTPPE HGWDPRGDPG RWGELQLGRL 420
QGKLLQSWLC FPDQGWDPNA NLRKLLPGIK 450 
Gene Ontology
 GO:0005856; C:cytoskeleton; IEA:InterPro. 
Interpro
 IPR019749; Band_41_domain.
 IPR019750; Band_41_fam.
 IPR014352; FERM/acyl-CoA-bd_prot_3-hlx.
 IPR019748; FERM_central.
 IPR019747; FERM_CS.
 IPR000299; FERM_domain.
 IPR018979; FERM_N.
 IPR018980; FERM_PH-like_C.
 IPR011993; PH_like_dom. 
Pfam
 PF09380; FERM_C
 PF00373; FERM_M
 PF09379; FERM_N 
SMART
 SM00295; B41 
PROSITE
 PS00660; FERM_1
 PS00661; FERM_2
 PS50057; FERM_3 
PRINTS
 PR00935; BAND41.