CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042065
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 LOC100718592 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Cavia porcellus (Guinea pig) 
NCBI Taxa ID
 10141 
Lysine Modification
Position
Peptide
Type
References
237DNSSRFGKFIRINFDacetylation[1]
Reference
 [1] The cardiac acetyl-lysine proteome.
 Foster DB, Liu T, Rucker J, O'Meally RN, Devine LR, Cole RN, O'Rourke B.
 PLoS One. 2013;8(7):e67513. [PMID: 23844019] 
Functional Description
  
Sequence Annotation
  
Keyword
 Actin-binding; ATP-binding; Coiled coil; Complete proteome; Motor protein; Myosin; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1960 AA 
Protein Sequence
MAQQAADKYL YVDKNFINNP LAQADWAAKK LVWVPSDKSG FEPASLKEEV GEEAIVELVE 60
NGKKVKVNKD DIQKMNPPKF SKVEDMAELT CLNEASVLHN LKERYYSGLI YTYSGLFCVV 120
INPYKNLPIY SEEIVEMYKG KKRHEMPPHI YAITDTAYRS MMQDREDQSI LCTGESGAGK 180
TENTKKVIQY LAHVASSHKS KKDQGELERQ LLQANPILEA FGNAKTVKND NSSRFGKFIR 240
INFDVNGYIV GANIETYLLE KSRAIRQAKE ERTFHIFYYL LSGAGEHLKT DLLLEPYNKY 300
RFLSNGHVTI PGQQDKDMFQ ETMEAMRIMG IPEEEQMGLL RVISGVLQLG NIVFKKERNT 360
DQASMPDNTA AQKVSHLLGI NVTDFTRGIL TPRIKVGRDY VQKAQTKEQA DFAIEALAKA 420
TYERMFRWLV LRINKALDKT KRQGASFIGI LDIAGFEIFD LNSFEQLCIN YTNEKLQQLF 480
NHTMFILEQE EYQREGIEWN FIDFGLDLQP CIDLIEKPAG PPGILALLDE ECWFPKATDK 540
SFVEKVMQEQ GTHPKFQKPK QLKDKADFCI IHYAGKVDYK ADEWLMKNMD PLNDNIATLL 600
HQSSDKFVSE LWKDVDRIIG LDQVAGMSET ALPGAFKTRK GMFRTVGQLY KEQLAKLMAT 660
LRNTNPNFVR CIIPNHEKKA GKLDPHLVLD QLRCNGVLEG IRICRQGFPN RVVFQEFRQR 720
YEILTPNSIP KGFMDGKQAC VLMIKALELD SNLYRIGQSK VFFRAGVLAH LEEERDLKIT 780
DVIIGFQACC RGYLARKAFA KRQQQLTAMK VLQRNCAAYL KLRNWQWWRL FTKVKPLLQV 840
SRQEEEMLAK EEELVKVREK QLAAENKLTE METLQSQLMA EKLQLQEQLQ AETELCAEAE 900
ELRARLTAKK QELEEICHDL EARVEEEEER CQHLQAEKKK MQQNIQELEE QLEEEESARQ 960
KLQLEKVTTE AKLKKLEEDQ IIMEDQNCKL AKEKKLLEDR IAEFTTNLME EEEKSKSLAK 1020
LKNKHEAMIT DLEERLRREE KQRQELEKTR RKLEGDSTDL SDQIAELQAQ IAELKMQLAK 1080
KEEELQTALA RVEEEAAQKN MALKKIRELE SQISELQEDL ESERASRNKA EKQKRDLGEE 1140
LEALKTELED TLDSTAAQQE LRSKREQEVN ILKKTLEEEA RTHEAQIQEM RQKHSQAVEE 1200
LAEQLEQTKR VKATLEKAKQ TLENERGELA NEVKVLMQGK GDSEHKRKKV EAQLQELQVK 1260
FNEGERVRTE LADKVTKLQV ELDNVTGLLN QSDSKSSKLT KDFSALESQL QDTQELLQEE 1320
NRQKLSLSTK LKQMEDEKNS FKEQLEEEEE AKHNLEKQIA TLQAQVTDMK KKMEDGVGCL 1380
ETSEEARRKL QKDLEGLSQR HEEKVAAYDK LEKTKTRLQQ ELDDLLVDLD HQRQSVSNLE 1440
KKQKKFDQLL AEEKTISAKY AEERDRAEAE AREKETKALS LARALEEAME QKAELERLNK 1500
QFRTEMEDLM SSKDDVGKSV HELEKSKRAL EQQVEEMKTQ LEELEDELQA TEDAKLRLEV 1560
NLQAMKAQFE RDLQGRDEQS EEKKKQLVRQ VREMEAELED EKKQRSLAVA ARKKLEMDLK 1620
DLEAHIDTAN KNREEAIKQL RKLQAQMKDC MRELEDTRAS REEILAQAKE NEKKLKSMEA 1680
EMIQLQEELA AAERAKRQAQ QERDELADEI ANSSGKGALA LEEKRRLEAR IAQLEEELEE 1740
EQGNTELIND RLKKANLQID QINTDLNLER SHAQKNENAR QQLERQNKEL KVKLQEMEGT 1800
VKSKYKASIT ALEAKIAQLE EQLDNETKER QAASKQVRRA EKRLKDVLLQ VEDERRNAEQ 1860
YKDQADKAST RLKQLKRQLE EAEEEAQRAN ASRRKLQREL EDATETADAM NREVSSLKNK 1920
LRRGDMPFVV PRRMARKGTG DCSDEEVDGK ADGAEAKPTE 1960 
Gene Ontology
 GO:0005826; C:actomyosin contractile ring; IEA:Compara.
 GO:0005913; C:cell-cell adherens junction; IEA:Compara.
 GO:0032154; C:cleavage furrow; IEA:Compara.
 GO:0030863; C:cortical cytoskeleton; IEA:Compara.
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0070062; C:extracellular vesicular exosome; IEA:Compara.
 GO:0001772; C:immunological synapse; IEA:Compara.
 GO:0008305; C:integrin complex; IEA:Compara.
 GO:0016460; C:myosin II complex; IEA:Compara.
 GO:0031594; C:neuromuscular junction; IEA:Compara.
 GO:0001726; C:ruffle; IEA:Compara.
 GO:0008180; C:signalosome; IEA:Compara.
 GO:0005819; C:spindle; IEA:Compara.
 GO:0001725; C:stress fiber; IEA:Compara.
 GO:0001931; C:uropod; IEA:Compara.
 GO:0030898; F:actin-dependent ATPase activity; IEA:Compara.
 GO:0043531; F:ADP binding; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0000146; F:microfilament motor activity; IEA:Compara.
 GO:0031532; P:actin cytoskeleton reorganization; IEA:Compara.
 GO:0030048; P:actin filament-based movement; IEA:Compara.
 GO:0001525; P:angiogenesis; IEA:Compara.
 GO:0043534; P:blood vessel endothelial cell migration; IEA:Compara.
 GO:0016337; P:cell-cell adhesion; IEA:Compara.
 GO:0000910; P:cytokinesis; IEA:Compara.
 GO:0051295; P:establishment of meiotic spindle localization; IEA:Compara.
 GO:0001768; P:establishment of T cell polarity; IEA:Compara.
 GO:0001701; P:in utero embryonic development; IEA:Compara.
 GO:0000212; P:meiotic spindle organization; IEA:Compara.
 GO:0006509; P:membrane protein ectodomain proteolysis; IEA:Compara.
 GO:0030224; P:monocyte differentiation; IEA:Compara.
 GO:0007520; P:myoblast fusion; IEA:Compara.
 GO:0030220; P:platelet formation; IEA:Compara.
 GO:0015031; P:protein transport; IEA:Compara.
 GO:0008360; P:regulation of cell shape; IEA:Compara.
 GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
 GO:0032796; P:uropod organization; IEA:Compara. 
Interpro
 IPR000048; IQ_motif_EF-hand-BS.
 IPR027401; Myosin-like_IQ_dom.
 IPR001609; Myosin_head_motor_dom.
 IPR004009; Myosin_N.
 IPR002928; Myosin_tail.
 IPR027417; P-loop_NTPase.
 IPR016137; Regulat_G_prot_signal_superfam. 
Pfam
 PF00612; IQ
 PF00063; Myosin_head
 PF02736; Myosin_N
 PF01576; Myosin_tail_1 
SMART
 SM00015; IQ
 SM00242; MYSc 
PROSITE
 PS50096; IQ 
PRINTS
 PR00193; MYOSINHEAVY.