| Tag | Content |
|---|
| CPLM ID | CPLM-011162 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | U3 small nucleolar RNA-associated protein 5 |
Protein Synonyms/Alias | U3 snoRNA-associated protein 5; U three protein 5; U3 protein 5 required for transcription; t-UTP5 |
Gene Name | UTP5 |
Gene Synonyms/Alias | YDR398W; D9509.17 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 348 | ADRDLHGKDLASATN | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs). |
Sequence Annotation | REPEAT 14 54 WD 1.
REPEAT 55 98 WD 2.
REPEAT 186 225 WD 3.
REPEAT 227 266 WD 4.
REPEAT 340 389 WD 5.
REPEAT 471 511 WD 6. |
Keyword | Complete proteome; Nucleus; Reference proteome; Repeat; Ribonucleoprotein; Ribosome biogenesis; rRNA processing; Transcription; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 643 AA |
Protein Sequence | MDSPVLQSAY DPSGQYLCYV TVALDKQRVG VQPTQRATSS GVDTVWNENF LYLEDSKLKV 60
TCLKWVNLAS SDTVAIILGM NNGEIWLYSV LANEVTYKFT TGNSYEIKDI DLMGNQLWCI 120
DSSDAFYQFD LLQFKLLQHF RINNCVQLNK LTIVPAGDSV AQLLVASHSI SLIDIEEKKV 180
VMTFPGHVSP VSTLQVITNE FFISGAEGDR FLNVYDIHSG MTKCVLVAES DIKELSHSGQ 240
ADSIAVTTED GSLEIFVDPL VSSSTKKRGN KSKKSSKKIQ IVSKDGRKVP IYNAFINKDL 300
LNVSWLQNAT MPYFKNLQWR EIPNEYTVEI SLNWNNKNKS ADRDLHGKDL ASATNYVEGN 360
ARVTSGDNFK HVDDAIKSWE RELTSLEQEQ AKPPQANELL TETFGDKLES STVARISGKK 420
TNLKGSNLKT ATTTGTVTVI LSQALQSNDH SLLETVLNNR DERVIRDTIF RLKPALAVIL 480
LERLAERIAR QTHRQGPLNV WVKWCLIIHG GYLVSIPNLM STLSSLHSTL KRRSDLLPRL 540
LALDARLDCT INKFKTLNYE AGDIHSSEPV VEEDEDDVEY NEELDDAGLI EDGEESYGSE 600
EEEEGDSDNE EEQKHTSSKQ DGRLETEQSD GEEEAGYSDV EME 643 |
Gene Ontology | GO:0033553; C:rDNA heterochromatin; IDA:SGD. GO:0032040; C:small-subunit processome; IDA:SGD. GO:0034455; C:t-UTP complex; IDA:SGD. GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD. GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; IMP:SGD. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
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