| Tag | Content |
|---|
| CPLM ID | CPLM-020875 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | ADP-ribosylation factor GTPase-activating protein 3 |
Protein Synonyms/Alias | ARF GAP 3 |
Gene Name | Arfgap3 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 280 | SSLRLAYKDLEISRK | acetylation | [1] |
|
Reference | [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways. Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y. Mol Cell. 2013 Jun 27;50(6):919-30. [ PMID: 23806337] |
Functional Description | GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity). |
Sequence Annotation | DOMAIN 10 126 Arf-GAP.
ZN_FING 25 48 C4-type.
MOD_RES 231 231 Phosphoserine (By similarity).
MOD_RES 331 331 Phosphoserine (By similarity).
MOD_RES 377 377 Phosphoserine (By similarity).
MOD_RES 460 460 Phosphoserine (By similarity). |
Keyword | Complete proteome; Cytoplasm; ER-Golgi transport; Golgi apparatus; GTPase activation; Membrane; Metal-binding; Phosphoprotein; Protein transport; Reference proteome; Transport; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 523 AA |
Protein Sequence | MGDPSKQDIL AIFKRLRSVP TNKVCFDCGA KNPSWASISY GVFLCIDCSG SHRSLGVHLS 60
FIRSTELDSN WSWFQLRCMQ VGGNSNASSF FHQHGCATKD TNAKYNSRAA QLYREKIKTL 120
ATQATRRHGT DLWLDSCAAP PVSPPPKEED FFASHASLEV SGAMQASAQP ESASSTPWGL 180
ETTPEKHEGG PGQGPSVEGL NTPGKAAPEV SSIIKKKPNQ AKKGLGAKKG SLGAQKLTNT 240
SFTEIEKQAQ AVDKRKEQED LARGAPKEES IVSSLRLAYK DLEISRKKDE RLNLSGQKKV 300
EAERLGMGFG SCRSGISHSV TSDMQTIEQE SPTLAKPRRK YQEDPEDSYF SSSSKWSEQS 360
SRYFDDPMEL RSSSFSSWDD GADSYWKKDS SRDPEPAMRS TGSSDRPSAR RKPEYEPIGS 420
TDEAQKKFGN VKAISSDMYF GIQAQTDFET RARLERLSTS SSISSADLFD EQRKQTAGNY 480
NLSNVLPNAP DMAQFKQGVR SVAGKLSVFA NGVMTSIQDR YGS 523 |
Gene Ontology | GO:0005829; C:cytosol; ISS:UniProtKB. GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. GO:0008060; F:ARF GTPase activator activity; ISS:UniProtKB. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0009306; P:protein secretion; ISS:UniProtKB. GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |