CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015226
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GTPase IMAP family member 6 
Protein Synonyms/Alias
 Immunity-associated nucleotide 2 protein; IAN-2; hIAN2; Immunity-associated nucleotide 6 protein; IAN-6; hIAN6 
Gene Name
 GIMAP6 
Gene Synonyms/Alias
 IAN2; IAN6 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
53MGKTGSGKSATGNSIubiquitination[1, 2]
69GRDVFESKLSTRPVTubiquitination[1, 2]
246TQQNFRLKELQERQVubiquitination[1]
289AHRCLLGKADL****ubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
 NP_BIND 47 55 GTP (By similarity).
 NP_BIND 164 166 GTP (By similarity).
 BINDING 68 68 GTP (By similarity).
 BINDING 201 201 GTP (By similarity).  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; GTP-binding; Nucleotide-binding; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 292 AA 
Protein Sequence
MEEEEYEQIP QENPPEELSQ DPVLELSGGL REKEQKTPRR LRLILMGKTG SGKSATGNSI 60
LGRDVFESKL STRPVTKTSQ RRSREWAGKE LEVIDTPNIL SPQVSPEVAD AICQAIVLSA 120
PGPHAVLLVT QLGRFTDEDQ QVVRRLQEVF GVGVLGHTIL VFTRKEDLAG GSLEDYVRET 180
NNQALAWLDV TLARRHCGFN NRAQGEEQEA QLRELMEKVE AIMWENEGDY YSNKAYQYTQ 240
QNFRLKELQE RQVSQGQGSE DVPGEESWLE GLSQIQKESE EAHRCLLGKA DL 292 
Gene Ontology
 GO:0005829; C:cytosol; IDA:UniProtKB.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW. 
Interpro
 IPR006703; AIG1.
 IPR027417; P-loop_NTPase. 
Pfam
 PF04548; AIG1 
SMART
  
PROSITE
  
PRINTS