CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027929
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DEAD box helicase, UAP56 
Protein Synonyms/Alias
  
Gene Name
 UAP56 
Gene Synonyms/Alias
 PFB0445c 
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
58TVHTGGFKDFFLKPEacetylation[1]
192NKHIKLFKEDNIPHIacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Helicase; Hydrolase; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 457 AA 
Protein Sequence
MASMDHNAQD ELVDYEDDEN ILDSKDVKGN LGNNILNNNN KGGAMRGSYA TVHTGGFKDF 60
FLKPELLRAI SESGFEHPSE VQQETIPAAI TGTDILCQAK SGMGKTAVFV LSILQQLDTN 120
ENQDMQDTKE MNNDNNNNGD NKFVRCLGLA HTRELAYQIK NEFDRFSKYL KNVRCEVVYG 180
GISMNKHIKL FKEDNIPHII IGTPGRILAL IREKYLITDK IQHFVLDECD KCLEKLDMRS 240
DVQKIFISTP LKKQVMFFSA TMAKEMRDVC KKFLQNPVEI FIDDEAKLKL HGLLQHYVKL 300
QEKDKTRKLI EILDALEFNQ VIIFVKSVTR AITLDKLLTE CNFPSIAIHG GLEQQERIER 360
YDKFKKFENR ILVSTDLFGR GIDIERVNIV INYDMPENSD SYLHRVGRAG RFGTKGLAVT 420
FVSSQEDTLA LNEVQTRFEV AISEMPNKID CNEYINQ 457 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004004; F:ATP-dependent RNA helicase activity; ISS:GeneDB_Pfalciparum.
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 
Interpro
 IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase.
 IPR014014; RNA_helicase_DEAD_Q_motif. 
Pfam
 PF00270; DEAD
 PF00271; Helicase_C 
SMART
 SM00487; DEXDc
 SM00490; HELICc 
PROSITE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER
 PS51195; Q_MOTIF 
PRINTS