Tag | Content |
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CPLM ID | CPLM-012102 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Golgin subfamily A member 4 |
Protein Synonyms/Alias | 256 kDa golgin; Golgin-245; Protein 72.1; Trans-Golgi p230 |
Gene Name | GOLGA4 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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492 | HEKELARKEQELTKK | ubiquitination | [1] | 827 | QLAQLQQKLLDLETE | ubiquitination | [1] | 2173 | TEFEYLRKVLFEYMM | ubiquitination | [1] |
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Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1. |
Sequence Annotation | DOMAIN 2168 2215 GRIP. REGION 133 203 Interaction with MACF1. MOD_RES 41 41 Phosphoserine (By similarity). MOD_RES 71 71 Phosphoserine. MOD_RES 78 78 Phosphoserine. MOD_RES 89 89 Phosphoserine. MOD_RES 266 266 Phosphoserine. MOD_RES 2223 2223 Phosphothreonine. |
Keyword | 3D-structure; Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Golgi apparatus; Membrane; Phosphoprotein; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 2230 AA |
Protein Sequence | MFKKLKQKIS EEQQQLQQAL APAQASSNSS TPTRMRSRTS SFTEQLDEGT PNRESGDTQS 60 FAQKLQLRVP SVESLFRSPI KESLFRSSSK ESLVRTSSRE SLNRLDLDSS TASFDPPSDM 120 DSEAEDLVGN SDSLNKEQLI QRLRRMERSL SSYRGKYSEL VTAYQMLQRE KKKLQGILSQ 180 SQDKSLRRIA ELREELQMDQ QAKKHLQEEF DASLEEKDQY ISVLQTQVSL LKQRLRNGPM 240 NVDVLKPLPQ LEPQAEVFTK EENPESDGEP VVEDGTSVKT LETLQQRVKR QENLLKRCKE 300 TIQSHKEQCT LLTSEKEALQ EQLDERLQEL EKIKDLHMAE KTKLITQLRD AKNLIEQLEQ 360 DKGMVIAETK RQMHETLEMK EEEIAQLRSR IKQMTTQGEE LREQKEKSER AAFEELEKAL 420 STAQKTEEAR RKLKAEMDEQ IKTIEKTSEE ERISLQQELS RVKQEVVDVM KKSSEEQIAK 480 LQKLHEKELA RKEQELTKKL QTREREFQEQ MKVALEKSQS EYLKISQEKE QQESLALEEL 540 ELQKKAILTE SENKLRDLQQ EAETYRTRIL ELESSLEKSL QENKNQSKDL AVHLEAEKNK 600 HNKEITVMVE KHKTELESLK HQQDALWTEK LQVLKQQYQT EMEKLREKCE QEKETLLKDK 660 EIIFQAHIEE MNEKTLEKLD VKQTELESLS SELSEVLKAR HKLEEELSVL KDQTDKMKQE 720 LEAKMDEQKN HHQQQVDSII KEHEVSIQRT EKALKDQINQ LELLLKERDK HLKEHQAHVE 780 NLEADIKRSE GELQQASAKL DVFQSYQSAT HEQTKAYEEQ LAQLQQKLLD LETERILLTK 840 QVAEVEAQKK DVCTELDAHK IQVQDLMQQL EKQNSEMEQK VKSLTQVYES KLEDGNKEQE 900 QTKQILVEKE NMILQMREGQ KKEIEILTQK LSAKEDSIHI LNEEYETKFK NQEKKMEKVK 960 QKAKEMQETL KKKLLDQEAK LKKELENTAL ELSQKEKQFN AKMLEMAQAN SAGISDAVSR 1020 LETNQKEQIE SLTEVHRREL NDVISIWEKK LNQQAEELQE IHEIQLQEKE QEVAELKQKI 1080 LLFGCEKEEM NKEITWLKEE GVKQDTTLNE LQEQLKQKSA HVNSLAQDET KLKAHLEKLE 1140 VDLNKSLKEN TFLQEQLVEL KMLAEEDKRK VSELTSKLKT TDEEFQSLKS SHEKSNKSLE 1200 DKSLEFKKLS EELAIQLDIC CKKTEALLEA KTNELINISS SKTNAILSRI SHCQHRTTKV 1260 KEALLIKTCT VSELEAQLRQ LTEEQNTLNI SFQQATHQLE EKENQIKSMK ADIESLVTEK 1320 EALQKEGGNQ QQAASEKESC ITQLKKELSE NINAVTLMKE ELKEKKVEIS SLSKQLTDLN 1380 VQLQNSISLS EKEAAISSLR KQYDEEKCEL LDQVQDLSFK VDTLSKEKIS ALEQVDDWSN 1440 KFSEWKKKAQ SRFTQHQNTV KELQIQLELK SKEAYEKDEQ INLLKEELDQ QNKRFDCLKG 1500 EMEDDKSKME KKESNLETEL KSQTARIMEL EDHITQKTIE IESLNEVLKN YNQQKDIEHK 1560 ELVQKLQHFQ ELGEEKDNRV KEAEEKILTL ENQVYSMKAE LETKKKELEH VNLSVKSKEE 1620 ELKALEDRLE SESAAKLAEL KRKAEQKIAA IKKQLLSQME EKEEQYKKGT ESHLSELNTK 1680 LQEREREVHI LEEKLKSVES SQSETLIVPR SAKNVAAYTE QEEADSQGCV QKTYEEKISV 1740 LQRNLTEKEK LLQRVGQEKE ETVSSHFEMR CQYQERLIKL EHAEAKQHED QSMIGHLQEE 1800 LEEKNKKYSL IVAQHVEKEG GKNNIQAKQN LENVFDDVQK TLQEKELTCQ ILEQKIKELD 1860 SCLVRQKEVH RVEMEELTSK YEKLQALQQM DGRNKPTELL EENTEEKSKS HLVQPKLLSN 1920 MEAQHNDLEF KLAGAEREKQ KLGKEIVRLQ KDLRMLRKEH QQELEILKKE YDQEREEKIK 1980 QEQEDLELKH NSTLKQLMRE FNTQLAQKEQ ELEMTIKETI NKAQEVEAEL LESHQEETNQ 2040 LLKKIAEKDD DLKRTAKRYE EILDAREEEM TAKVRDLQTQ LEELQKKYQQ KLEQEENPGN 2100 DNTQLAQKTT LISDSKLKEQ EFREQIHNLE DRLKKYEKNV YATTVGTPYK GGNLYHTDVS 2160 LFGEPTEFEY LRKVLFEYMM GRETKTMAKV ITTVLKFPDD QTQKILERED ARLMFTSPRS 2220 GIF 2223 |
Gene Ontology | GO:0005794; C:Golgi apparatus; IDA:UniProtKB. GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. GO:0005802; C:trans-Golgi network; TAS:ProtInc. GO:0043001; P:Golgi to plasma membrane protein transport; IDA:UniProtKB. GO:0000042; P:protein targeting to Golgi; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |