| Tag | Content |
|---|
| CPLM ID | CPLM-018487 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Epsin-3 |
Protein Synonyms/Alias | EPS-15-interacting protein 3 |
Gene Name | Epn3 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 86 | TLLDYLLKTGSERVA | ubiquitination | [1] | | 107 | LYTIQTLKDFQYIDR | ubiquitination | [1] | | 117 | QYIDRDGKDQGVNVR | ubiquitination | [1] | | 135 | KQVMALLKDEERLRQ | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | |
Sequence Annotation | DOMAIN 12 144 ENTH.
REPEAT 202 221 UIM 1.
REPEAT 229 248 UIM 2.
REPEAT 315 317 1.
REPEAT 338 340 2.
REPEAT 365 367 3.
REPEAT 381 383 4.
REPEAT 398 400 5.
REPEAT 523 525 1.
REPEAT 536 538 2.
REPEAT 633 635 3.
REGION 315 400 5 X 3 AA repeats of [DE]-P-W.
REGION 523 635 3 X 3 AA repeats of N-P-F.
BINDING 8 8 Phosphatidylinositol lipid headgroup (By
BINDING 11 11 Phosphatidylinositol lipid headgroup (By
BINDING 25 25 Phosphatidylinositol lipid headgroup (By
BINDING 30 30 Phosphatidylinositol lipid headgroup (By
BINDING 63 63 Phosphatidylinositol lipid headgroup (By
BINDING 73 73 Phosphatidylinositol lipid headgroup (By |
Keyword | Complete proteome; Cytoplasm; Cytoplasmic vesicle; Lipid-binding; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 636 AA |
Protein Sequence | MTTSALRRQV KNIVHNYSEA EIKVREATSN DPWGPPSSLM SEIADLTFNT VAFAEVMGMV 60
WRRLNDSGKN WRHVYKALTL LDYLLKTGSE RVAHQCRENL YTIQTLKDFQ YIDRDGKDQG 120
VNVREKVKQV MALLKDEERL RQERTHALKT KERMALEGMG IGSGQLGYSR RSRGSPSSYT 180
SASSSPRYAS DLEQARPQTS GEEELQLQLA LAMSREEAER PVPPASHRDE DLQLQLALSL 240
SRQEHEKGVR SWKGDDSPVA NGAEPAGQRR QRDREPEREE RKEEEKLKTS QSSILDLADI 300
FAPAPALPST HCSADPWDIP GLRPNTEPSG SSWGPSADPW SPVPSGNALS RSQPWDLLPT 360
LSSSEPWGRT PVLPSGPPIA DPWAPSSPTR KLPSTGADPW GASMETSDTS ALGGASPFDP 420
FAKPLESTEP KESRDSAQAL PTGKSPSTVE LDPFGDSSPS CKQNGMKEPE ALDLGVLGEA 480
LPQQPGKEAR PCRTPESFLG PSASSLVNLD SLVKAPLAAR TRNPFLTGLG VPSPTNPFGA 540
GDQGRPTLNQ MRTGSPALGL PPGGPVGAPV GSMTYSASLP LPLSSVPVGA TLPASVSVFP 600
QAGAFAPPPA SLPQPLLPTS GPMGPLPPQA GTNPFL 636 |
Gene Ontology | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell. GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. GO:0008289; F:lipid binding; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |