CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043477
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 E3 ubiquitin-protein ligase AMFR 
Protein Synonyms/Alias
  
Gene Name
 AMFR 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
68DSMQAARKLPCGHLFubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 288 AA 
Protein Sequence
WLSMASLVIF MQLRYLFHEV QRRIRRHKNY LRVVGNMEAR FAVATPEELA VNNDDCAICW 60
DSMQAARKLP CGHLFHNSCL RSWLEQDTSC PTCRMSLNIA DNNRVREEHQ GENLDENLVP 120
VAAAEGRPRL NQHNHFFHFD GDDSSMRVTA PEDVPVGQEV EVVDSDTDAP DLWSRIASWL 180
PSFSVEVMHT TNILGITQAS NSQLNAMAHQ IQEMFPQVPY HLVLQDLQLT RSVEITTDNI 240
LEGRIQVPFP TQRSDSIRPA LNSPVERPSS DQEEGETSAQ TERVPLDL 288 
Gene Ontology
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0016567; P:protein ubiquitination; IEA:GOC. 
Interpro
 IPR026608; Amfr.
 IPR003892; CUE.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF02845; CUE
 PF13639; zf-RING_2 
SMART
 SM00546; CUE
 SM00184; RING 
PROSITE
 PS51140; CUE
 PS50089; ZF_RING_2 
PRINTS