CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020648
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATP-binding cassette sub-family B member 8, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 Abcb8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
495VGQSGGGKTTVASLLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
 DOMAIN 130 419 ABC transmembrane type-1.
 DOMAIN 454 691 ABC transporter.
 NP_BIND 489 496 ATP (Potential).  
Keyword
 ATP-binding; Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Nucleotide-binding; Reference proteome; Transit peptide; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 717 AA 
Protein Sequence
MLVHLFRFGI RGGPVPGWSL QSLRFQTFSA ARSSDDRLSS HLLRTVAQLR VQLRAHLPRA 60
PPASHWSPSA WCWVGGTLVV PAVLWQHPRL CLIALCEAKE SPPAQPTRAP ELRFNWKLFW 120
HFLHPHLLAL GAAIVLALGA ALVNVQIPLL LGQLVEIVAK YTRDHMGSFV SESRKLSVQL 180
LLLYGVQGLL TFGYLVLLSH IGERMAMDMR KALFSSLLRQ DIAFFDAKKT GQLVSRLTTD 240
VQEFKSSFKL VISQGLRSCT QVIGSLVSLS MLSPRLTLML AVVTPALMGV GTLMGSGLRK 300
LSRQCQEQIA RATGVADEAL GNVRTVRAFA MEKREEERYQ AELESCCCKA EELGRGIALF 360
QGLSNIAFNC MVLGTLFIGG SLVAGQQLKG GDLMSFLVAS QTVQRSMASL SVLFGQVVRG 420
LSAGARVFEY MALSPVIPLT GGYCIPNKDI RGSITFQNVT FSYPCRPGFN VLKDFTLKLP 480
SGKIVALVGQ SGGGKTTVAS LLERFYDPEA GSVTLDGHDL RTLNPSWLRG QVIGFISQEP 540
VLFATTIMEN IRFGKLDASD EEVYTAAREA NAHEFISSFP DGYSTVVGER GTTLSGGQKQ 600
RLAIARALIK QPTVLILDEA TSALDAESER VVQEALDRAS AGRTVLVIAH RLSTVRAAHS 660
IIVMANGQVC EAGTHEELLK KGGLYSELIR RQTLDASLTS TPPAEKPEDP KSCQSKA 717 
Gene Ontology
 GO:0016021; C:integral to membrane; IBA:RefGenome.
 GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IBA:RefGenome. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR017940; ABC_transporter_type1.
 IPR001140; ABC_transptr_TM_dom.
 IPR011527; ABC_transptrTM_dom_typ1.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00664; ABC_membrane
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS50929; ABC_TM1F
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS