| Tag | Content |
|---|
| CPLM ID | CPLM-037448 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Receptor-type tyrosine-protein phosphatase kappa |
Protein Synonyms/Alias | |
Gene Name | PTPRK |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 227 | GRDAVHNKLWLQRRN | ubiquitination | [1] | | 262 | FRLQEVTKTDQDLYR | ubiquitination | [1] | | 397 | MRTPKTLKIAEIQAR | ubiquitination | [1] | | 1448 | VKTLRNSKPNMVEAP | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | |
Sequence Annotation | |
Keyword | Complete proteome; Hydrolase; Protein phosphatase; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1472 AA |
Protein Sequence | MDTTAAAALP AFVALLLLSP WPLLGSAQGQ FSAGGCTFDD GPGACDYHQD LYDDFEWVHV 60
SAQEPHYLPP EMPQGSYMIV DSSDHDPGEK ARLQLPTMKE NDTHCIDFSY LLYSQKGLNP 120
GTLNILVRVN KGPLANPIWN VTGFTGRDWL RAELAVSTFW PNEYQVIFEA EVSGGRSGYI 180
AIDDIQVLSY PCDKSPHFLR LGDVEVNAGQ NATFQCIATG RDAVHNKLWL QRRNGEDIPV 240
AQTKNINHRR FAASFRLQEV TKTDQDLYRC VTQSERGSGV SNFAQLIVRE PPRPIAPPQL 300
LGVGPTYLLI QLNANSIIGD GPIILKEVEY RMTSGSWTET HAVNAPTYKL WHLDPDTEYE 360
IRVLLTRPGE GGTGLPGPPL ITRTKCAEPM RTPKTLKIAE IQARRIAVDW ESLGYNITRC 420
HTFNVTICYH YFRGHNESKA DCLDMDPKAP QHVVNHLPPY TNVSLKMILT NPEGRKESEE 480
TIIQTDEDVP GPVPVKSLQG TSFENKIFLN WKEPLDPNGI ITQYEISYSS IRSFDPAVPV 540
AGPPQTVSNL WNSTHHVFMH LHPGTTYQFF IRASTVKGFG PATAINVTTN ISAPTLPDYE 600
GVDASLNETA TTITVLLRPA QAKGAPISAY QIVVEELHPH RTKREAGAME CYQVPVTYQN 660
AMSGGAPYYF AAELPPGNLP EPAPFTVGDN RTYQGFWNPP LAPRKGYNIY FQAMSSVEKE 720
TKTQCVRIAT KAAATEEPEV IPDPAKQTDR VVKIAGISAG ILVFILLLLV VILIVKKRRS 780
YYSYSYYLKL AKKRKDAMGN TRQEMTHMVN AMDRSYADQS TLHAEDPLSI TFMDQHNFSP 840
RLPNDPLVPT AVLVPITDEN HSATAESSRL LDVPRYLCEG TESPYQTGQL HPAIRVADLL 900
QHINLMKTSD SYGFKEEYES FFEGQSASWD VAKKDQNRAK NRYGNIIAYD HSRVILQPVE 960
DDPSSDYINA NYIDIWLYRD GYQRPSHYIA TQGPVHETVY DFWRMIWQEQ SACIVMVTNL 1020
VEVGRVKCYK YWPDDTEVYG DFKVTCVEME PLAEYVVRTF TLERRGYNEI REVKQFHFTG 1080
WPDHGVPYHA TGLLSFIRRV KLSNPPSAGP IVVHCSAGAG RTGCYIVIDI MLDMAEREGV 1140
VDIYNCVKAL RSRRINMVQT EEQYIFIHDA ILEACLCGET AIPVCEFKAA YFDMIRIDSQ 1200
TNSSHLKDEF QTLNSVTPRL QAEDCSIACL PRNHDKNRFM DMLPPDRCLP FLITIDGESS 1260
NYINAALMDS YRQPAAFIVT QYPLPNTVKD FWRLVYDYGC TSIVMLNEVD LSQGCPQYWP 1320
EEGMLRYGPI QVECMSCSMD CDVINRIFRI CNLTRPQEGY LMVQQFQYLG WASHREVPGS 1380
KRSFLKLILQ VEKWQEECEE GEGRTIIHCL NGGGRSGMFC AIGIVVEMVK RQNVVDVFHA 1440
VKTLRNSKPN MVEAPEQYRF CYDVALEYLE SS 1472 |
Gene Ontology | GO:0016020; C:membrane; IEA:InterPro. GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro. GO:0035335; P:peptidyl-tyrosine dephosphorylation; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |