| Tag | Content |
|---|
| CPLM ID | CPLM-001676 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Echinoderm microtubule-associated protein-like 2 |
Protein Synonyms/Alias | EMAP-2; HuEMAP-2 |
Gene Name | EML2 |
Gene Synonyms/Alias | EMAP2; EMAPL2 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 157 | AKKEGKTKEVIFSVE | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity). |
Sequence Annotation | REPEAT 103 152 WD 1.
REPEAT 157 200 WD 2.
REPEAT 203 242 WD 3.
REPEAT 250 288 WD 4.
REPEAT 292 331 WD 5.
REPEAT 375 414 WD 6.
REPEAT 416 455 WD 7.
REPEAT 458 497 WD 8.
REPEAT 504 543 WD 9.
REPEAT 571 610 WD 10.
REPEAT 616 648 WD 11. |
Keyword | Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Polymorphism; Reference proteome; Repeat; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 649 AA |
Protein Sequence | MSLDDNLSGT SGMEVDDRVS ALEQRLQLQE DELAVLKAAL ADALRRLRAC EEQGAALRAR 60
GTPKGRAPPR LGTTASVCQL LKGLPTRTPL NGSGPPRRVG GYATSPSSPK KEATSGRSSV 120
RRYLSPERLA SVRREDPRSR TTSSSSNCSA KKEGKTKEVI FSVEDGSVKM FLRGRPVPMM 180
IPDELAPTYS LDTRSELPSC RLKLEWVYGY RGRDCRANLY LLPTGEIVYF VASVAVLYSV 240
EEQRQRHYLG HNDDIKCLAI HPDMVTIATG QVAGTTKEGK PLPPHVRIWD SVSLSTLHVL 300
GLGVFDRAVC CVGFSKSNGG NLLCAVDESN DHMLSVWDWA KETKVVDVKC SNEAVLVATF 360
HPTDPTVLIT CGKSHIYFWT LEGGSLSKRQ GLFEKHEKPK YVLCVTFLEG GDVVTGDSGG 420
NLYVWGKGGN RITQAVLGAH DGGVFGLCAL RDGTLVSGGG RDRRVVLWGS DYSKLQEVEV 480
PEDFGPVRTV AEGHGDTLYV GTTRNSILQG SVHTGFSLLV QGHVEELWGL ATHPSRAQFV 540
TCGQDKLVHL WSSDSHQPLW SRIIEDPARS AGFHPSGSVL AVGTVTGRWL LLDTETHDLV 600
AIHTDGNEQI SVVSFSPDGA YLAVGSHDNL VYVYTVDQGG RKVSRLGKCS GHSSFITHLD 660
WAQDSSCFVT NSGDYEILYW DPATCKQITS ADAVRNMEWA TATCVLGFGV FGIWSEGADG 720
TDINAVARSH DGKLLASADD FGKVHLFSYP CCQPRALSHK YGGHSSHVTN VAFLWDDSMA 780
LTTGGKDTSV LQWRVV 796 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW. GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA. GO:0005874; C:microtubule; IEA:UniProtKB-KW. GO:0005875; C:microtubule associated complex; TAS:ProtInc. GO:0003824; F:catalytic activity; IEA:InterPro. GO:0008152; P:metabolic process; IEA:GOC. GO:0007605; P:sensory perception of sound; TAS:ProtInc. GO:0007601; P:visual perception; TAS:ProtInc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |