UniProt Accession

 G3P_MYCPN; P75358 

Genbank Protein ID

 U00089 

Genbank Nucleotide ID

 AAB96059.1 

Protein Name

 Glyceraldehyde-3-phosphate dehydrogenase 

Protein Synonyms/Alias

 GAPDH 

Gene Name

 gapA 

Gene Synonyms/Alias

 gap; MPN_430; MP411 

Created Date

 July 27, 2013 

Organism

 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 

NCBI Taxa ID

 272634 

Lysine Modification

Position	Peptide	Type	References
60	DSAHGEFKKKVVAKD	acetylation	[1]
62	AHGEFKKKVVAKDNT	acetylation	[1]
66	FKKKVVAKDNTLMID	acetylation	[1]
74	DNTLMIDKKKVLVFS	acetylation	[1]
143	VVYNVNHKIINAEDK	acetylation	[1]
219	PTTTGAAKAIGLVVP	acetylation	[1]
267	EQINQAMKKAASASF	acetylation	[1]

Reference

 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 

Functional Description

  

Sequence Annotation

 NP_BIND 17 18 NAD (By similarity).
 REGION 156 158 Glyceraldehyde 3-phosphate binding (By
 REGION 215 216 Glyceraldehyde 3-phosphate binding (By
 ACT_SITE 157 157 Nucleophile (By similarity).
 BINDING 39 39 NAD (By similarity).
 BINDING 83 83 NAD; via carbonyl oxygen (By similarity).
 BINDING 187 187 Glyceraldehyde 3-phosphate (By
 BINDING 202 202 Glyceraldehyde 3-phosphate (By
 BINDING 238 238 Glyceraldehyde 3-phosphate (By
 BINDING 319 319 NAD (By similarity).  

Keyword

 Complete proteome; Cytoplasm; Glycolysis; NAD; Oxidoreductase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 337 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004365; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; IEA:EC.
 GO:0051287; F:NAD binding; IEA:InterPro.
 GO:0050661; F:NADP binding; IEA:InterPro.
 GO:0006096; P:glycolysis; IEA:UniProtKB-UniPathway. 

Interpro

 IPR020831; GlycerAld/Erythrose_P_DH.
 IPR020830; GlycerAld_3-P_DH_AS.
 IPR020829; GlycerAld_3-P_DH_cat.
 IPR020828; GlycerAld_3-P_DH_NAD(P)-bd.
 IPR006424; Glyceraldehyde-3-P_DH_1.
 IPR016040; NAD(P)-bd_dom. 

Pfam

 PF02800; Gp_dh_C
 PF00044; Gp_dh_N 

SMART

 SM00846; Gp_dh_N 

PROSITE

 PS00071; GAPDH 

PRINTS

 PR00078; G3PDHDRGNASE.